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Tocris™ Tetrabenazine

Potent inhibitor of vesicular monoamine transport

$179.63 - $746.94

Specifications

Product Type Tetrabenazine
Inhibitors Tetrabenazine
Molecular Weight 317.2
Purity >98
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Disclaimers:

For Research Use Only



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
217510 Tocris™
217510
10mg Each for $179.63
217550 Tocris™
217550
50mg Each for $746.94
Specifications

Description

Potent inhibitor of vesicular monoamine uptake; depletes stores of dopamine, serotonin and noradrenalin. Binds with high affinity (IC50= 3.2nM) to vesicular monoamine transporter (VMAT) in chromaffin granule membranes and displays higher affinity for VMAT2 than VMAT1. Also reported to block dopamine receptors. Causes behavioral depression; inhibits locomotor activity and produces hypothermia upon systemic administration in rats and mice.
  • Chemical Name: (3R,11bR)-rel-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-2H-benzo[a]quinolizin-2-one
  • Formula: C19H27NO3
  • CAS Number: 58-46-8
  • Solubility: Soluble to 30mM in ethanol and to 100mM in DMSO
  • Purity: >98
Description & Specifications

Specifications

Tetrabenazine
Tetrabenazine
317.2
>98