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Tocris™ Tetrabenazine

Potent inhibitor of vesicular monoamine transport

$173.50 - $718.43

Specifications

Product Type Tetrabenazine
Inhibitors Tetrabenazine
Molecular Weight 317.2
Purity >98
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 Disclaimers

For Research Use Only

Products
Catalog Number Mfr. No. Quantity Price Quantity    

217510

 
tocris™
2175/10
10mg Each for $173.50

217550

 
tocris™
2175/50
50mg Each for $718.43
Description & Specifications

Specifications

Product Type Tetrabenazine
Inhibitors Tetrabenazine
Molecular Weight 317.2
Purity >98

Potent inhibitor of vesicular monoamine uptake; depletes stores of dopamine, serotonin and noradrenalin. Binds with high affinity (IC50= 3.2nM) to vesicular monoamine transporter (VMAT) in chromaffin granule membranes and displays higher affinity for VMAT2 than VMAT1. Also reported to block dopamine receptors. Causes behavioral depression; inhibits locomotor activity and produces hypothermia upon systemic administration in rats and mice.

  • Chemical Name: (3R,11bR)-rel-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-2H-benzo[a]quinolizin-2-one
  • Formula: C19H27NO3
  • CAS Number: 58-46-8
  • Solubility: Soluble to 30mM in ethanol and to 100mM in DMSO
  • Purity: >98