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TdT Mouse, Clone: 7UNA8U6, eBioscience™

Mouse Monoclonal Antibody

$143.55 - $361.05

Specifications

Antigen TdT
Clone 7UNA8U6
Host Species Mouse
Gene Alias Terminal-deoxynucleotidyl transferase
Species Reactivity Human, Mouse, Rat
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

501122805

 
affymetrix
14973980
25μg Each for $143.55

501122806

 
affymetrix
14973982
100μg Each for $361.05
Description & Specifications

Specifications

Antigen TdT
Clone 7UNA8U6
Host Species Mouse
Gene Alias Terminal-deoxynucleotidyl transferase
Species Reactivity Human, Mouse, Rat
Applications Immunohistochemistry
Applications Immunohistochemistry (Formalin/Paraffin)
Applications Western Blotting
Regulatory Status RUO
Conjugate Unlabeled
Format Purified
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.5mg/mL

The monoclonal antibody 7UNA8U6 reacts with human, mouse, and rat TdT. TdT, or terminal-deoxynucleotidyl transferase, is a 60kDa polymerase responsible for the template-independent addition of N-nucleotides at gene segment junctions of developing lymphocytes. Expression is found in the nucleus of immature lymphocytes but not in mature lymphocytes or non-lymphoid cells. TdT plays a critical role during TCR and Ig gene rearrangement and functions to increase the diversity of the lymphocyte repertoire through the addition of N-nucleotides onto the ends of newly formed P-nucleotides. After positive selection, expression of TdT becomes decreased or absent. Expression of TdT has been shown to be present in lymphoma or lymphoblastic leukemia cells.