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TdT Mouse anti-Mouse, PE, Clone: 19-3, eBioscience™

Mouse Monoclonal Antibody

$187.05 - $433.55

Specifications

Antigen TdT
Clone 19-3
Host Species Mouse
Gene Alias terminal deoxynucleotidyl transferase
Species Reactivity Mouse
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5010902

 
affymetrix
12-5846-80
25μg Each for $187.05

5010903

 
affymetrix
12-5846-82
100μg Each for $433.55
Description & Specifications

Specifications

Antigen TdT
Clone 19-3
Host Species Mouse
Gene Alias terminal deoxynucleotidyl transferase
Species Reactivity Mouse
Applications Flow Cytometry (Intracellular Staining)
Regulatory Status RUO
Conjugate PE
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.2mg/mL

This 19-3 monoclonal antibody recognizes human and mouse terminal-deoxynucleotidyl transferase (TdT), a 60kDa polymerase responsible for the template-independent addition of N-nucleotides at gene segment junctions of developing lymphocytes. Expression is found in the nucleus of immature lymphocytes but not in mature lymphocytes or non-lymphoid cells. Tdt plays a critical role during TCR and Ig gene rearrangement. Regulation of expression in the mouse thymus correlates with T cell selection; decreased or absent after positive selection. Additionally Tdt has been shown to be present in lymphoma or lymphoblastic leukemia cells.