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Invitrogen™ TAOK1 Recombinant Human Protein 
TAOK1 is a serine/threonine-protein kinase. Recombinant human TAOK1 (1-314) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Manufacturer: Invitrogen™ LSPV6416
Description
TAOK1 is involved in regulation of the p38-containing stress-responsive MAP kinase pathway and extracellular signal-regulated protein kinase (ERK) kinases (MEKs). The activation of and binding to MEK3 by TAOK1 implicates TAOK1 in the regulation of the p38-containing stress-responsive MAP kinase pathway. A microtubule affinity-regulating kinase kinase, TAOK1 (also known as MARKK) is an important regulator of mitotic progression, required for both chromosome congression and checkpoint-induced anaphase delay.
- Validated in LanthaScreen™ Kinase Binding Assay
- Protocols available for simple use and optimized performance
- Multiple pack sizes available for convenient use
Specifications
| Target & Lead Identification & Validation|Kinase Biology|Kinase Proteins & Expression Reagents|Protein Biology|Enzyme & Protein Activity Assays|Kinase Activity|Protein Assays and Analysis|Industrial & Applied Science|Pharma & Biopharma | |
| 62.1kDa | |
| Store at -68 to -85°C. Aliquot at first use to avoid multiple freeze-thaws. | |
| Kinase Assay | |
| Human | |
| GST Tag |
| 50mM Tris-HCl pH 7.5, 150mM NaCl, 0.1mM EGTA, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol | |
| 100μg | |
| PSK2, MARKK, MAP3K16, FLJ14314, KIAA1361 | |
| aa 1-314 | |
| Yes |