missing translation for 'onlineSavingsMsg'
Learn More
Please login to your online account to display your discounted pricing

Alfa Aesar™ Tamoxifen citrate

Inhibitor of protein kinase C and induces apoptosis in cancer cells

$274.50 - $692.41

Chemical Identifiers

CAS 54965-24-1
Molecular Formula C32H37NO8
Molecular Weight (g/mol) 563.647
MDL Number MFCD00058321
InChI Key FQZYTYWMLGAPFJ-OQKDUQJOSA-N
Synonym tamoxifen citrate, istubal, tamoxifen citrate, zitazonium, unii-7frv7310n6, i.c.i. 46474 citrate, tamoxifen citrate salt, farmifeno, ginarsan, jenoxifen
PubChem CID 2733525
ChEBI CHEBI:9397
IUPAC Name 2-[4-[(Z)-1,2-diphenylbut-1-enyl]phenoxy]-N,N-dimethylethanamine;2-hydroxypropane-1,2,3-tricarboxylic acid
SMILES CCC(=C(C1=CC=CC=C1)C2=CC=C(C=C2)OCCN(C)C)C3=CC=CC=C3.C(C(=O)O)C(CC(=O)O)(C(=O)O)O
View More Specs

Products 2
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
AAJ6095503 View Documents Alfa Aesar™
J6095503
1g Each for $274.50
 
AAJ6095506 View Documents Alfa Aesar™
J6095506
5g Each for $692.41
 
Description

Description

Applications
Tamoxifen citrate is used as an antiestrogen with potent anti-cancer and PKC inhibitory activities. Tamoxifen Citrate functions as an estrogen receptor antagonist in breast tissue. Tamoxifen Citrate is an agonist towards this receptor in tissues of the endometrium. Tamoxifen Citrate inhibits DNA synthesis and transcription by recruiting co-repressors, which stop estrogen from interacting with genes. When combined with PAX2, Tamoxifen Citrate can inhibit the proliferation of ERBB2. It is also a high affinity activator of the GPR30 receptor. Tamoxifen Citrate is an activator of Estrogen Receptor.

Solubility
Soluble in methanol (50 mg/ml with heat) or ethanol (10 mg/ml with sonication); very slightly soluble in water (0.3 mg/L @ 20°C; the pH is approximately 3.0-3.5), 0.02 N HCl (0.2 mg/ml @ 37°C)4, acetone ,chloroform,and DMSO(100mM)

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: 2 - 8°C. Keep away from strong oxidizing agents.
Specifications

Chemical Identifiers

54965-24-1
563.647
FQZYTYWMLGAPFJ-OQKDUQJOSA-N
2733525
2-[4-[(Z)-1,2-diphenylbut-1-enyl]phenoxy]-N,N-dimethylethanamine;2-hydroxypropane-1,2,3-tricarboxylic acid
C32H37NO8
MFCD00058321
tamoxifen citrate, istubal, tamoxifen citrate, zitazonium, unii-7frv7310n6, i.c.i. 46474 citrate, tamoxifen citrate salt, farmifeno, ginarsan, jenoxifen
CHEBI:9397
CCC(=C(C1=CC=CC=C1)C2=CC=C(C=C2)OCCN(C)C)C3=CC=CC=C3.C(C(=O)O)C(CC(=O)O)(C(=O)O)O

Specifications

Light Sensitive and Hygroscopic
1g
C32H37NO8
14,9048
FQZYTYWMLGAPFJ-OQKDUQJOSA-N
2-[4-[(Z)-1,2-diphenylbut-1-enyl]phenoxy]-N,N-dimethylethanamine;2-hydroxypropane-1,2,3-tricarboxylic acid
2733525
563.65
Tamoxifen citrate
White
54965-24-1
MFCD00058321
tamoxifen citrate, istubal, tamoxifen citrate, zitazonium, unii-7frv7310n6, i.c.i. 46474 citrate, tamoxifen citrate salt, farmifeno, ginarsan, jenoxifen
CCC(=C(C1=CC=CC=C1)C2=CC=C(C=C2)OCCN(C)C)C3=CC=CC=C3.C(C(=O)O)C(CC(=O)O)(C(=O)O)O
563.647
CHEBI:9397
Powder
Safety and Handling

Safety and Handling

GHS H Statement
H350-H360-H362-H302
May cause cancer.
May damage fertility or the unborn child.
May cause harm to breast-fed children.
Harmful if swallowed.

GHS P Statement
P263-P260-P281-P301+P312-P405-P501a
Avoid contact during pregnancy/while nursing.
Do not breathe dust/fume/gas/mist/vapors/spray.
Use personal protective equipment as required.
IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.

Danger

RTECSNumber : KH2387000

Recommended Storage : 2° to 8°C