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Thermo Scientific™ Lab Vision™ Synuclein Ab-2, Mouse Monoclonal Antibody


Provide accurate, reproducible results Thermo Scientific™ Synuclein Ab-2, Mouse Monoclonal Antibody.

Manufacturer: thermo scientific™ lab vision™  MS1572P1ABX

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Catalog No. MS1572P1ABX

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Description & Specifications

Specifications

Immunogen Human recombinant alpha-synuclein
Applications Immunohistochemistry (Paraffin)
Applications Immunoprecipitation
Applications Western Blotting
Host Species Mouse
Format Concentrated
Quantity 100µL
Antigen Synuclein Ab-2
Isotype IgG1
Cross Reactivity Human
Regulatory Status RUO
Clone syn211
Type Primary
Research Discipline Neuroscience
Concentration 1mg/mL
Conjugate Unlabeled
Classification Monoclonal
Formulation Ab without BSA/Azide (Frozen)

Provide accurate, reproducible results Thermo Scientific™ Synuclein Ab-2, Mouse Monoclonal Antibody.

Synnuclein family of proteins is abundantly expressed in neuronal cytosol and presynaptic terminals. In vertebrates they are encoded by three different genes. Synucleins have been specifically implemented in three major diseases: Alzheimer's (AD), Parkinson's (PD) and breast cancer. In AD, a peptide derived from α-synuclein forms an intrinsic component of plaque amyloid. In PD, an alpha synuclein accumulates in Lewy bodies. An allele of α synuclein has been linked to many familial cases of PD. In breast cancer increased expression of γ synuclein correlates with the disease progression. Synucleins appear to be involved in the membrane plasticity in developing song control system of songbirds.

Host Species: Mouse

Clone: syn211

Isotype: IgG1

Species Reactivity: Human. Does not react with mouse and rat. Others not known.

Epitope: Not determined

Immunogen: Human recombinant α-synuclein

Molecular Weight: ∽14kDa

Positive Control: Brain

Cellular Localization: Neuronal cytosol and presynaptic terminals

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunoprecipitation

Note:

USA: RUO; Int'l: RUO