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Thermo Scientific™ Lab Vision™ Surfactant Protein B (Precursor) Ab-1, Mouse Monoclonal Antibody


Provide accurate, reproducible results with the Thermo Scientific™ Surfactant Protein B (Precursor) Ab-1, Mouse Monoclonal Antibody.

Manufacturer: thermo scientific™ lab vision™  MS704P1ABX

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Catalog No. MS704P1ABX

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Description & Specifications

Specifications

Antigen Surfactant Protein B (Precursor) Ab-1
Applications Immunofluorescence
Applications Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone SPB01; same as 1-2-A5-9
Concentration 1mg/mL
Conjugate Unlabeled
Cross Reactivity Human
Cross Reactivity Rat
Format Concentrated
Formulation Ab without BSA/Azide (Frozen)
Host Species Mouse
Immunogen Recombinant pro-surfactant protein B
Isotype IgG2a kappa
Quantity 100µL
Regulatory Status RUO
Research Discipline Cancer and Tumor Biology
Type Primary

Provide accurate, reproducible results with the Thermo Scientific™ Surfactant Protein B (Precursor) Ab-1, Mouse Monoclonal Antibody.

Pulmonary surfactant is a complex mixture of phospholipids and proteins that is secreted from type II cells in alveoli and reduces the surface tension at the alveolar air-liquid interface, providing alveolar stability necessary for normal ventillation. Four distinct proteins isolated from pulmonary surfactant are termed surfactant proteins A, B, C, and D. SP-A (28-36kDa) and SP-D (43kDa) are collagenous carbohydrate-binding proteins, whereas SP-B (8-9kDa) and SP-C (4kDa) are non-collagenous hydrophobic proteins. SP-B is expressed in pulmonary adenocarcinomas with acinar, papillary, bronchioloalveolar, and solid growth patterns. Squamous cell and large cell carcinomas of the lung and nonpulmonary adenocarcinomas do not express SP-B. ProSP-B is glycosylated in the Golgi apparatus and undergoes carboxy- and amino-terminal proteolysis by a cathepsin D-like protease.

Host Species: Mouse

Clone: SPB01; same as 1-2-A5-9

Isotype: IgG2a/κ

Species Reactivity: Human and Rat. Others not known.

Epitope: Not determined

Immunogen: Recombinant prosurfactant protein B

Molecular Weight: 42-46kDa

Positive Control: Lung adenocarcinoma

Cellular Localization: Cytoplasmic

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Immunofluorescence

Note:

USA: RUO; Int'l: RUO