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Alfa Aesar™ Suramin hexasodium salt, 98+%

$785.65 - $2,096.45

Chemical Identifiers

CAS 129-46-4
Molecular Formula C51H34N6Na6O23S6
Molecular Weight (g/mol) 1429.151
MDL Number MFCD00210217
InChI Key VAPNKLKDKUDFHK-UHFFFAOYSA-H
Synonym suramin sodium, suramin hexasodium, suramin hexasodium salt, suramin sodium salt, antrypol, moranyl, naganinum, naphuride sodium, fourneau 309, suramine sodium salt
PubChem CID 8514
IUPAC Name hexasodium;8-[[4-methyl-3-[[3-[[3-[[2-methyl-5-[(4,6,8-trisulfonatonaphthalen-1-yl)carbamoyl]phenyl]carbamoyl]phenyl]carbamoylamino]benzoyl]amino]benzoyl]amino]naphthalene-1,3,5-trisulfonate
SMILES CC1=C(C=C(C=C1)C(=O)NC2=C3C(=CC(=CC3=C(C=C2)S(=O)(=O)[O-])S(=O)(=O)[O-])S(=O)(=O)[O-])NC(=O)C4=CC(=CC=C4)NC(=O)NC5=CC=CC(=C5)C(=O)NC6=C(C=CC(=C6)C(=O)NC7=C8C(=CC(=CC8=C(C=C7)S(=O)(=O)[O-])S(=O)(=O)[O-])S(=O)(=O)[O-])C.[Na+].[Na+].[Na+].[Na+].[Na+].[Na+]
View More Specs

Products 3
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
AAJ61707MD View Documents Alfa Aesar™
J61707MD
250mg Each for $785.65
 
AAJ61707ME View Documents Alfa Aesar™
J61707ME
500mg Each for $1,258.70
 
AAJ6170703 View Documents Alfa Aesar™
J6170703
1g Each for $2,096.45
 
Description

Description

Applications
Suramin Sodium has been observed as a potent inhibitor of melanoma HPA (heparanase) and tumor cell metastasis. Inhibition of NAD+-dependent deacetylase SIRT1 with an IC50 of 2.6 μM along with SIRT5 has also been observed. Suramin Sodium has been recorded to antagonize EDG-3 (S1P3) selectively. Suramin Sodium is an inhibitor of A cyclase, FGF-1, FGF-2, IL-1, IL-4, PDGF, PC-PLD, PKC, SH-PTP, TERT, TGF beta 1, Topo I, Topo II and VEGF. It is used as a G protein uncoupler and inhibitor of PDGF, EGF, TGF-β, SIRT1 and SIRT5. It also blocks calmodulin binding to recognition sites and G protein coupling to G protein-coupled receptors. Increases open probability of ryanodine receptor (RyR) channels. Anticancer and antiviral agent.

Solubility
Soluble in water and saline. Sparingly soluble in 95% bethanol

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Keep away from strong oxidizing agents.
Specifications

Chemical Identifiers

129-46-4
1429.151
VAPNKLKDKUDFHK-UHFFFAOYSA-H
8514
CC1=C(C=C(C=C1)C(=O)NC2=C3C(=CC(=CC3=C(C=C2)S(=O)(=O)[O-])S(=O)(=O)[O-])S(=O)(=O)[O-])NC(=O)C4=CC(=CC=C4)NC(=O)NC5=CC=CC(=C5)C(=O)NC6=C(C=CC(=C6)C(=O)NC7=C8C(=CC(=CC8=C(C=C7)S(=O)(=O)[O-])S(=O)(=O)[O-])S(=O)(=O)[O-])C.[Na+].[Na+].[Na+].[Na+].[Na+].[Na+]
C51H34N6Na6O23S6
MFCD00210217
suramin sodium, suramin hexasodium, suramin hexasodium salt, suramin sodium salt, antrypol, moranyl, naganinum, naphuride sodium, fourneau 309, suramine sodium salt
hexasodium;8-[[4-methyl-3-[[3-[[3-[[2-methyl-5-[(4,6,8-trisulfonatonaphthalen-1-yl)carbamoyl]phenyl]carbamoyl]phenyl]carbamoylamino]benzoyl]amino]benzoyl]amino]naphthalene-1,3,5-trisulfonate

Specifications

White
129-46-4
MFCD00210217
14,9006
Soluble in water and saline; Sparingly soluble in 95% bethanol
CC1=C(C=C(C=C1)C(=O)NC2=C3C(=CC(=CC3=C(C=C2)S(=O)(=O)[O-])S(=O)(=O)[O-])S(=O)(=O)[O-])NC(=O)C4=CC(=CC=C4)NC(=O)NC5=CC=CC(=C5)C(=O)NC6=C(C=CC(=C6)C(=O)NC7=C8C(=CC(=CC8=C(C=C7)S(=O)(=O)[O-])S(=O)(=O)[O-])S(=O)(=O)[O-])C.[Na+].[Na+].[Na+].[Na+].[Na+].[Na+]
1429.151
1429.16
≥98%
250mg
C51H34N6Na6O23S6
3694087
suramin sodium, suramin hexasodium, suramin hexasodium salt, suramin sodium salt, antrypol, moranyl, naganinum, naphuride sodium, fourneau 309, suramine sodium salt
VAPNKLKDKUDFHK-UHFFFAOYSA-H
hexasodium;8-[[4-methyl-3-[[3-[[3-[[2-methyl-5-[(4,6,8-trisulfonatonaphthalen-1-yl)carbamoyl]phenyl]carbamoyl]phenyl]carbamoylamino]benzoyl]amino]benzoyl]amino]naphthalene-1,3,5-trisulfonate
8514
Powder
Suramin hexasodium salt
Safety and Handling

Safety and Handling

RTECSNumber : QM7000000

Recommended Storage : 2° to 8°C