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Tocris™ SR 48692

Selective non-peptide NTS1 antagonist

$320.01 - $1,348.18

Specifications

Product Type SR 48692
Inhibitors SR 48692
Molecular Weight 587.07
Purity >98
View More Specs

 Disclaimers

For Research Use Only

Products
Catalog Number Mfr. No. Quantity Price Quantity    

372110R

 
tocris™
3721/10
10mg Each for $320.01

372150R

 
tocris™
3721/50
50mg Each for $1,348.18
Description & Specifications

Specifications

Product Type SR 48692
Inhibitors SR 48692
Molecular Weight 587.07
Purity >98

Neurotensin antagonist; selective for NTS1 over NTS2 (apparent affinity, Ke, is 36nM for NTS1). Competitively inhibits binding of [125I]-neurotensin to HT29 and N1E115 cell membranes (IC50 values are 15.3 and 20.4nM respectively). Orally bioavailable.

  • Chemical Name: 2-[[[1-(7-Chloro-4-quinolinyl)-5-(2,6-dimethoxyphenyl)-1H-pyrazol-3-yl]carbonyl]amino]-tricyclo[3.3.1.13,7]decane-2-carboxylic acid
  • Formula: C32H31ClN4O5
  • CAS Number: 146362-70-1
  • Solubility: Soluble to 20mM in DMSO
  • Purity: >98