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Thermo Scientific™ Lab Vision™ sm (Smith Antigen) Ab-1, Mouse Monoclonal Antibody

Provide accurate, reproducible results with the Thermo Scientific™ sm (Smith Antigen) Ab-1, Mouse Monoclonal Antibody.

$255.55 - $1,406.49

Specifications

Antigen sm (Smith Antigen) Ab-1
Clone Y12
Applications Immunofluorescence
Applications Immunohistochemistry (Paraffin)
Applications Western Blotting
View More Specs
Products
Catalog Number Mfr. No. Formulation Quantity Price Quantity    

MS450B

 
thermo scientific™ lab vision™
MS-450-B
Biotinylated Ab with BSA and Azide 1mL Each for $1,406.49

MS450B0

 
thermo scientific™ lab vision™
MS-450-B0
Biotinylated Ab with BSA and Azide 100µL Each for $346.12

MS450B1

 
thermo scientific™ lab vision™
MS-450-B1
Biotinylated Ab with BSA and Azide 500µL Each for $941.78

MS450P

 
thermo scientific™ lab vision™
MS-450-P
Purified Ab with BSA and Azide 1mL Each for $1,100.67

MS450P0

 
thermo scientific™ lab vision™
MS-450-P0
Purified Ab with BSA and Azide 100µL Each for $255.55

MS450P1

 
thermo scientific™ lab vision™
MS-450-P1
Purified Ab with BSA and Azide 500µL Each for $714.67

MS450P1ABX

 
thermo scientific™ lab vision™
MS450P1ABX
Ab without BSA/Azide (Frozen) 100µL Each for $788.88

MS450PABX

 
thermo scientific™ lab vision™
MS-450-PABX
Ab Without BSA/Azide (Frozen) 200µL Each for $1,172.12

MS450R7

 
thermo scientific™ lab vision™
MS-450-R7
Ready-to-use for IHC (UVLP) 7mL Each for $679.20
Description & Specifications

Specifications

Antigen sm (Smith Antigen) Ab-1
Clone Y12
Applications Immunofluorescence
Applications Immunohistochemistry (Paraffin)
Applications Western Blotting
Applications Immunofluorescence
Applications Immunohistochemistry (Paraffin)
Applications Western Blotting
Applications Immunofluorescence
Applications Immunohistochemistry (Paraffin)
Applications Western Blotting
Classification Monoclonal
Cross Reactivity Drosophila
Cross Reactivity Human
Cross Reactivity Porcine
Cross Reactivity Rabbit
Cross Reactivity Rat
Cross Reactivity Drosophila
Cross Reactivity Human
Cross Reactivity Porcine
Cross Reactivity Rabbit
Cross Reactivity Rat
Cross Reactivity Drosophila
Cross Reactivity Human
Cross Reactivity Porcine
Cross Reactivity Rabbit
Cross Reactivity Rat
Cross Reactivity Drosophila
Cross Reactivity Human
Cross Reactivity Porcine
Cross Reactivity Rabbit
Cross Reactivity Rat
Cross Reactivity Drosophila
Cross Reactivity Human
Cross Reactivity Porcine
Cross Reactivity Rabbit
Cross Reactivity Rat
Host Species Mouse
Regulatory Status RUO
Research Discipline DNA Repair
Type Primary
Isotype IgG3 kappa

Provide accurate, reproducible results with the Thermo Scientific™ sm (Smith Antigen) Ab-1, Mouse Monoclonal Antibody.

The sm (Smith) is an autoantigen on a series of particles composed of RNA and protein. Unlike RNP, the sm antigen is resistant to RNase, but partially sensitive to trypsin. It is involved in the pathogenesis of Systemic lupus erythematosus (SLE). Antibodies to sm are found in 20-30% of patients with SLE.

Host Species: Mouse

Clone: Y12

Isotype: IgG3/κ

Species Reactivity: Human, Pig, Rabbit, Rat and Drosophila. Others not known.

Epitope: Not determined

Molecular Weight: ∽25kDa (predominant)

Positive Control: Ls174T cells, Tonsil

Cellular Localization: Nuclear Ab-1 recognizes cross-reactive epitopes on the B'/B and D polypeptides of Sm. Ab-1 precipitates the small nuclear RNAs U1, U2, U4, U5, and U6 providing direct evidence that the Sm antigen resides on all these RNA-protein complexes.

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunofluorescence
  • Affinity Purification
  • Electron Microscopy

Note:

USA: RUO; Int'l: RUO