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Thermo Scientific™ Lab Vision™ sm (Smith Antigen) Ab-1, Mouse Monoclonal Antibody

Provide accurate, reproducible results with the Thermo Scientific™ sm (Smith Antigen) Ab-1, Mouse Monoclonal Antibody.

$267.04 - $1,469.65

Specifications

Antigen sm (Smith Antigen) Ab-1
Clone Y12
Applications Immunofluorescence,Immunohistochemistry (Paraffin),Western Blotting,Immunofluorescence,Immunohistochemistry (Paraffin),Western Blotting,Immunofluorescence,Immunohistochemistry (Paraffin),Western Blotting
Classification Monoclonal
Host Species Murine
View More Specs


Products ${productFamilyLength}
Catalog Number Mfr. No. Formulation Quantity Price Quantity  
Catalog Number Mfr. No. Formulation Quantity Price Quantity  
MS450B Thermo Scientific™ Lab Vision™
MS450B
Biotinylated Ab with BSA and Azide 1mL Each for $1,469.65
MS450B0 Thermo Scientific™ Lab Vision™
MS450B0
Biotinylated Ab with BSA and Azide 100μL Each for $361.82
MS450B1 Thermo Scientific™ Lab Vision™
MS450B1
Biotinylated Ab with BSA and Azide 500μL Each for $984.18
MS450P Thermo Scientific™ Lab Vision™
MS450P
Purified Ab with BSA and Azide 1mL Each for $1,150.12
MS450P0 Thermo Scientific™ Lab Vision™
MS450P0
Purified Ab with BSA and Azide 100μL Each for $267.04
MS450P1 Thermo Scientific™ Lab Vision™
MS450P1
Purified Ab with BSA and Azide 500μL Each for $746.80
MS450P1ABX Thermo Scientific™ Lab Vision™
MS450P1ABX
Ab without BSA/Azide (Frozen) 100μL Each for $824.43
MS450PABX Thermo Scientific™ Lab Vision™
MS450PABX
Ab Without BSA/Azide (Frozen) 200μL Each for $1,224.71
MS450R7 Thermo Scientific™ Lab Vision™
MS450R7
Ready-to-use for IHC (UVLP) 7mL Each for $709.73
Specifications

Description

Provide accurate, reproducible results with the Thermo Scientific™ sm (Smith Antigen) Ab-1, Mouse Monoclonal Antibody.

The sm (Smith) is an autoantigen on a series of particles composed of RNA and protein. Unlike RNP, the sm antigen is resistant to RNase, but partially sensitive to trypsin. It is involved in the pathogenesis of Systemic lupus erythematosus (SLE). Antibodies to sm are found in 20-30% of patients with SLE.

Host Species: Mouse

Clone: Y12

Isotype: IgG3/κ

Species Reactivity: Human, Pig, Rabbit, Rat and Drosophila. Others not known.

Epitope: Not determined

Molecular Weight: ∽25kDa (predominant)

Positive Control: Ls174T cells, Tonsil

Cellular Localization: Nuclear Ab-1 recognizes cross-reactive epitopes on the B'/B and D polypeptides of Sm. Ab-1 precipitates the small nuclear RNAs U1, U2, U4, U5, and U6 providing direct evidence that the Sm antigen resides on all these RNA-protein complexes.

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunofluorescence
  • Affinity Purification
  • Electron Microscopy

Note:

USA: RUO; Int'l: RUO

Description & Specifications

Specifications

sm (Smith Antigen) Ab-1
Immunofluorescence,Immunohistochemistry (Paraffin),Western Blotting,Immunofluorescence,Immunohistochemistry (Paraffin),Western Blotting,Immunofluorescence,Immunohistochemistry (Paraffin),Western Blotting
Murine
DNA Repair
IgG3 kappa
Y12
Monoclonal
RUO
Primary