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Sino Biological™ SPP1 Recombinant Human Protein, His Tag DFS Item

This recombinant protein is expressed from a DNA sequence encoding the pro form of human SPP1 (NP_001035147.1) (Met 1-Asn 314)fused to a polyhistidine tag at the C-terminus

$79.54 - $644.70

Specifications

Purity >80% by SDS-PAGE
Purification Method PAGE
Endotoxin Concentration <1 EU/μg
Format Lyophilized
Gene Alias BNSP, BSPI, ETA-1, mgC110940, OPN
View More Specs

 Disclaimers

For Research Use Only. Not for use in diagnostic procedures.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

10352H08H25

DFS Item
 
life technologies
LS10352H08H25
5 x 5μg Each for $175.35

10352H08H5

DFS Item
 
life technologies
LS10352H08H5
5μg Each for $79.54

10352H08H50

DFS Item
 
life technologies
LS10352H08H50
50μg Each for $263.55

10352H08HL

DFS Item
 
life technologies
LS10352H08H250
5 x 50μg Each for $644.70
Description & Specifications

Specifications

Purity >80% by SDS-PAGE
Purification Method PAGE
Endotoxin Concentration <1 EU/μg
Format Lyophilized
Gene Alias BNSP, BSPI, ETA-1, mgC110940, OPN
Gene ID (Entrez) 6696

Secreted Phosphoprotein 1 (SPP1) recombinant human protein is supplied as a lyophilized powder. This protein is suitable for use in analysis of protein structure. In general, recombinant proteins can also be used as an immunogen, as a protein standard, or in cell biology research applications.&line-break;Background: Secreted phosphoprotein 1, is a member of the osteopontin family. It is an extracellular structural protein and therefore an organic component of bone. Secreted phosphoprotein 1 is expressed in bone, although it is also expressed in other tissues. Secreted phosphoprotein 1 acts as a cytokine which is involved in enhancing production of interferon-gamma and interleukin-12 and reducing production of interleukin-10. It is essential in the pathway that leads to type I immunity. Secreted phosphoprotein 1 has been implicated as an important factor in bone remodeling. Specifically, research suggests it plays a role in anchoring osteoclasts to the mineral matrix of bones. The fact that Secreted phosphoprotein 1 interacts with multiple cell surface receptors which are ubiquitously expressed makes it an active player in many physiological and pathological processes including wound healing, bone turnover, tumorigenesis, inflammation and ischemia. Therefore, manipulation of plasma Secreted phosphoprotein 1 levels may be useful in the treatment of autoimmune diseases, cancer metastasis, osteoporosis and some forms of stress.

  • N-terminal Sequence Analysis: IIe 17
  • Activity: The activity of this protein has not been tested
  • Formulation: lyophilized in PBS, pH 7.4, 5% mannitol, 5% trehalose, 0.02% Tween®-80
  • Reconstitution: Dissolve the protein in sterile double-distilled water to a concentration of 0.2mg/mL or lower; aliquot and use as soon as possible

Manufactured by Sino Biological (China).