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Sino Biological™ NRG1 Recombinant Human Protein, hIgG1-Fc Tag DFS Item


This recombinant protein was expressed from a DNA sequence encoding the EGF-like domain (Thr 176-Lys 246) of human NRG1 (Q02297-6) fused to the Fc region of human IgG1 at the N-terminus

Manufacturer: life technologies  LS11609H01H5

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 Disclaimers

For Research Use Only. Not for use in diagnostic procedures.

Catalog No. 11609H01H5

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Description & Specifications

Specifications

Storage Requirements Store at -20°C. Store aliquots under sterile conditions at -20°C. Avoid repeated freeze-thaw cycles. Expires one year from date of receipt when stored as instructed.
Purity ≥85% by SDS-PAGE
Format Lyophilized
Protein Subtype Other Growth Factors
Protein Tag IgG1 Fc Tag
Validated Application Assay Standard
Endotoxin Concentration <1 EU/μg
Protein Family Growth Factors & Receptors
Expression System Mammalian
Gene Alias ARIA, GGF, GGF2, HGL, HRG, HRG1, HRGA, MST131, NDF, SMDF
Gene Symbol NRG1
Quantity 5μg
Molecular Weight 36.7kDa
For Use With (Application) Proteins, Expression, Isolation & Analysis; Enzyme & Protein Activity Assays; Protein Assay Controls, Reference Standards & Accessories
Common Name Neuregulin 1

Neuregulin 1 (NRG1), recombinant human protein is supplied as a lyophilized powder. It is suitable for use in protein studies such as protein structure analysis and protein-protein interactions. In general, recombinant proteins can also be used as an immunogen, as a protein standard, or in cell biology research applications.

  • Activity: Measured by its binding ability in a functional ELISA: 1. Immobilized Rhesus ErbB3 at 2μg/mL (100μL/well) can bind human NRG1 (isoform Beta1), the EC50 of human NRG1 (isoform Beta1) is typically 0.58μg/mL; 2. Immobilized human ErbB3 at 2μg/mL (100μL/well) can bind human NRG1 (isoform Beta1), the EC50 of human NRG1 (isoform Beta1) is typically 0.43μg/mL
  • Formulation: Lyophilized in 140mM NaCl, 2.7mM KCl, 10mM Na2HPO4, 1.8mM KH2PO4, pH 7.4, 5% Mannitol, 5% Trehalose, 0.02% Tween 80
  • Reconstitution: Dissolve the protein in sterile double distilled water to a concentration of 0.2mg/mL or lower; aliquot and use as soon as possible

This protein is manufactured by Sino Biological Inc.