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Sino Biological™ NRG1 Recombinant Human Protein, hIgG1-Fc Tag DFS Item


This recombinant protein was expressed from a DNA sequence encoding the EGF-like domain (Thr 176-Lys 246) of human NRG1 (Q02297-6) fused to the Fc region of human IgG1 at the N-terminus

Manufacturer: life technologies  LS11609H01H25

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 Disclaimers

For Research Use Only. Not for use in diagnostic procedures.

Catalog No. 11609H01H25

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Description & Specifications

Specifications

For Use With (Application) Proteins, Expression, Isolation & Analysis; Enzyme & Protein Activity Assays; Protein Assay Controls, Reference Standards & Accessories
Format Lyophilized
Molecular Weight 36.7kDa
Purity ≥85% by SDS-PAGE
Quantity 5 x 5μg
Storage Requirements Store at -20°C. Store aliquots under sterile conditions at -20°C. Avoid repeated freeze-thaw cycles. Expires one year from date of receipt when stored as instructed.
Protein Subtype Other Growth Factors
Endotoxin Concentration <1 EU/μg
Gene Alias ARIA, GGF, GGF2, HGL, HRG, HRG1, HRGA, MST131, NDF, SMDF
Common Name Neuregulin 1
Gene Symbol NRG1
Protein Tag IgG1 Fc Tag
Validated Application Assay Standard
Protein Family Growth Factors & Receptors
Expression System Mammalian

Neuregulin 1 (NRG1), recombinant human protein is supplied as a lyophilized powder. It is suitable for use in protein studies such as protein structure analysis and protein-protein interactions. In general, recombinant proteins can also be used as an immunogen, as a protein standard, or in cell biology research applications.

  • Activity: Measured by its binding ability in a functional ELISA: 1. Immobilized Rhesus ErbB3 at 2μg/mL (100μL/well) can bind human NRG1 (isoform Beta1), the EC50 of human NRG1 (isoform Beta1) is typically 0.58μg/mL; 2. Immobilized human ErbB3 at 2μg/mL (100μL/well) can bind human NRG1 (isoform Beta1), the EC50 of human NRG1 (isoform Beta1) is typically 0.43μg/mL
  • Formulation: Lyophilized in 140mM NaCl, 2.7mM KCl, 10mM Na2HPO4, 1.8mM KH2PO4, pH 7.4, 5% Mannitol, 5% Trehalose, 0.02% Tween 80
  • Reconstitution: Dissolve the protein in sterile double distilled water to a concentration of 0.2mg/mL or lower; aliquot and use as soon as possible

This protein is manufactured by Sino Biological Inc.