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Sino Biological™ IgG1-Fc Recombinant Human Protein DFS Item

This recombinant human protein is expressed from a DNA sequence encoding the human IgG1-Fc region (AAC82527.1), containing residues 99 to 330, including a 103 Cys/Ser mutation

$87.67 - $428.40

Specifications

Purity ≥95% by SDS-PAGE
Endotoxin Concentration <1 EU/μg
Format Lyophilized
Gene Alias Fc region of human immunoglobulin G1
View More Specs

 Disclaimers

For Research Use Only. Not for use in diagnostic procedures.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

10702HNAH25

DFS Item
 
life technologies
LS10702HNAH25
5 x 5μg Each for $147.00

10702HNAH5

DFS Item
 
life technologies
LS10702HNAH5
5μg Each for $87.67

10702HNAH50

DFS Item
 
life technologies
LS10702HNAH50
50μg Each for $190.05

10702HNAHL

DFS Item
 
life technologies
LS10702HNAH250
5 x 50μg Each for $428.40
Description & Specifications

Specifications

Purity ≥95% by SDS-PAGE
Endotoxin Concentration <1 EU/μg
Format Lyophilized
Gene Alias Fc region of human immunoglobulin G1

Immunoglobulin gamma-1 heavy chain constant region, partial (IgG1-Fc), recombinant human protein is supplied as a lyophilized powder. In general, recombinant proteins can be used as protein standard and in cell biology research applications.&line-break;Background: Immunoglobulin G (IgG) is synthesized and secreted by plasma B cells, and constitutes 75% of serum immunoglobulins in humans. IgG antibodies protect the body against the pathogens by agglutination and immobilization, complement activation, toxin neutralization, as well as the antibody-dependent cell-mediated cytotoxicity (ADCC). Recombinant IgG Fc is suggested to represent a potential anti-inflammatory drug for treatment of human autoimmune diseases.

  • N-terminal Sequence Analysis: Glu 99
  • Activity: 1. Measured by its ability to bind human CD16a-His (Mfr. No. 10389-H08H1) in a functional ELISA; 2. Measured by its ability to bind human CD16a-AVI-His (Mfr. No. 10389-H27H) in a functional ELISA; 3.Measured by its ability to bind human CD16a-His (Mfr. No. 10389-H08H) in a functional ELISA
  • Formulation: lyophilized in PBS, pH 7.4, 5% mannitol, 5% trehalose, and 0.02% Tween®-80
  • Reconstitution: Dissolve the protein in sterile double-distilled water to a concentration of 0.2mg/mL or lower; aliquot and use as soon as possible

Shipping Condition: Room Temperature. Manufactured by Sino Biological (China).