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Sino Biological™ IgG1-Fc Recombinant Human Protein DFS Item

This recombinant human protein is expressed from a DNA sequence encoding the human IgG1-Fc region (AAC82527.1), containing residues 99 to 330, including a 103 Cys/Ser mutation

Manufacturer: life technologies  LS10702HNAH5

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For Research Use Only. Not for use in diagnostic procedures.

Catalog No. 10702HNAH5


Description & Specifications


For Use With (Application) Proteins, Expression, Isolation & Analysis; Enzyme & Protein Activity Assays; Cell Analysis; Immunoassays; Protein Assay Controls, Reference Standards & Accessories; Build-Your-Own Immunoassay
Format Lyophilized
Molecular Weight 26kDa
Purity ≥95% by SDS-PAGE
Quantity 5μg
Storage Requirements Store at -20° to -70°C. Store aliquots under sterile conditions at -20°C. Avoid repeated freeze-thaw cycles. Expires one year from date of receipt when stored as instructed.
Structural Form Truncated/Recombinant
Protein Subtype Other Proteins
Endotoxin Concentration <1 EU/μg
Gene Alias Fc region of human immunoglobulin G1
Common Name Fc region of human immunoglobulin G1
Gene Symbol IgG1-Fc
Protein Tag IgG1 Fc Tag
Validated Application Assay Standard
Protein Family Growth Factors & Receptors
Expression System Mammalian

Immunoglobulin gamma-1 heavy chain constant region, partial (IgG1-Fc), recombinant human protein is supplied as a lyophilized powder. In general, recombinant proteins can be used as protein standard and in cell biology research applications.&line-break;Background: Immunoglobulin G (IgG) is synthesized and secreted by plasma B cells, and constitutes 75% of serum immunoglobulins in humans. IgG antibodies protect the body against the pathogens by agglutination and immobilization, complement activation, toxin neutralization, as well as the antibody-dependent cell-mediated cytotoxicity (ADCC). Recombinant IgG Fc is suggested to represent a potential anti-inflammatory drug for treatment of human autoimmune diseases.

  • N-terminal Sequence Analysis: Glu 99
  • Activity: 1. Measured by its ability to bind human CD16a-His (Mfr. No. 10389-H08H1) in a functional ELISA; 2. Measured by its ability to bind human CD16a-AVI-His (Mfr. No. 10389-H27H) in a functional ELISA; 3.Measured by its ability to bind human CD16a-His (Mfr. No. 10389-H08H) in a functional ELISA
  • Formulation: lyophilized in PBS, pH 7.4, 5% mannitol, 5% trehalose, and 0.02% Tween®-80
  • Reconstitution: Dissolve the protein in sterile double-distilled water to a concentration of 0.2mg/mL or lower; aliquot and use as soon as possible

Shipping Condition: Room Temperature