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Sino Biological™ ERBB4 Recombinant Human Protein (without Catalytic Activity Domain), hIgG1-Fc.His Tag DFS Item


This recombinant protein was expressed from a DNA sequence encoding the extracellular domain (Met 1-Pro 651) of human ERBB4 precursor (NP_001036064.1) fused to the His-tagged Fc region of human IgG1 at the C-terminus

Manufacturer: life technologies  LS10363H03H50

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 Disclaimers

For Research Use Only. Not for use in diagnostic procedures.

Catalog No. 10363H03H50

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Description & Specifications

Specifications

For Use With (Application) Proteins, Expression, Isolation & Analysis; Enzyme & Protein Activity Assays; Protein Assay Controls, Reference Standards & Accessories
Structural Form Truncated/Recombinant/Cell Surface Protein
Gene Symbol ERBB4
Molecular Weight 97.5kDa
Common Name v-erb-a erythroblastic leukemia viral oncogene homolog 4
Purity ≥85% by SDS-PAGE
Storage Requirements Store at -20° to -70°C. Store aliquots under sterile conditions at -20°C. Avoid repeated freeze-thaw cycles. Expires one year from date of receipt when stored as instructed.
KinaseFamily EGF Receptor (ErbB) Kinase Family
Validated Application Assay Standard
Format Lyophilized
Quantity 50μg
Gene ID (Entrez) 2066
Protein Tag His Tag/IgG1 Fc Tag
Protein Family Growth Factors & Receptors
Gene Alias HER4, mgC138404, p180erbB4, ERBB4
Protein Subtype Receptor Tyrosine Kinases|Growth Factor Receptors
Endotoxin Concentration <1 EU/μg
Expression System Mammalian

V-erb-a erythroblastic leukemia viral oncogene homolog 4 (ERBB4), recombinant human protein is supplied as a lyophilized powder. In general, recombinant proteins are suitable for use in studying protein-protein interactions, as a protein standard, or in cell biology research applications. Since this product is a truncated protein and does not contain intracellular catalytic activity domain, it is not suitable for use in enzyme activity studies.

  • Activity: Measured by its binding ability in a functional ELISA; immobilized human ERBB3-Fc at 1μg/well can bind biotinylated recombinant human NRG1 with a linear range of 0.032-0.16μg/mL
  • Formulation: Lyophilized in PBS, pH 7.4, 5% Mannitol, 5% Trehalose, and 0.02% Tween-80
  • Reconstitution: Dissolve the protein in sterile double distilled water to a concentration of 0.2mg/mL or lower; aliquot and use as soon as possible

Shipping Condition: Room Temperature. This protein is manufactured by Sino Biological Inc.