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Sino Biological™ ERBB4 Recombinant Human Protein (without Catalytic Activity Domain), hIgG1-Fc.His Tag DFS Item

This recombinant protein was expressed from a DNA sequence encoding the extracellular domain (Met 1-Pro 651) of human ERBB4 precursor (NP_001036064.1) fused to the His-tagged Fc region of human IgG1 at the C-terminus

Manufacturer: life technologies  LS10363H03H250

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For Research Use Only. Not for use in diagnostic procedures.

Catalog No. 10363H03HL


Description & Specifications


For Use With (Application) Proteins, Expression, Isolation & Analysis; Enzyme & Protein Activity Assays; Protein Assay Controls, Reference Standards & Accessories
Format Lyophilized
Gene ID (Entrez) 2066
Molecular Weight 97.5kDa
Purity ≥85% by SDS-PAGE
Quantity 5 x 50μg
Storage Requirements Store at -20° to -70°C. Store aliquots under sterile conditions at -20°C. Avoid repeated freeze-thaw cycles. Expires one year from date of receipt when stored as instructed.
Structural Form Truncated/Recombinant/Cell Surface Protein
Protein Subtype Receptor Tyrosine Kinases|Growth Factor Receptors
Endotoxin Concentration <1 EU/μg
Gene Alias HER4, mgC138404, p180erbB4, ERBB4
Common Name v-erb-a erythroblastic leukemia viral oncogene homolog 4
Gene Symbol ERBB4
Protein Tag His Tag/IgG1 Fc Tag
Validated Application Assay Standard
Protein Family Growth Factors & Receptors
Expression System Mammalian
KinaseFamily EGF Receptor (ErbB) Kinase Family

V-erb-a erythroblastic leukemia viral oncogene homolog 4 (ERBB4), recombinant human protein is supplied as a lyophilized powder. In general, recombinant proteins are suitable for use in studying protein-protein interactions, as a protein standard, or in cell biology research applications. Since this product is a truncated protein and does not contain intracellular catalytic activity domain, it is not suitable for use in enzyme activity studies.

  • Activity: Measured by its binding ability in a functional ELISA; immobilized human ERBB3-Fc at 1μg/well can bind biotinylated recombinant human NRG1 with a linear range of 0.032-0.16μg/mL
  • Formulation: Lyophilized in PBS, pH 7.4, 5% Mannitol, 5% Trehalose, and 0.02% Tween-80
  • Reconstitution: Dissolve the protein in sterile double distilled water to a concentration of 0.2mg/mL or lower; aliquot and use as soon as possible

Shipping Condition: Room Temperature. This protein is manufactured by Sino Biological Inc.