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Sino Biological™ ERBB2 Recombinant Human Protein (without Catalytic Activity Domain), hIgG1-Fc Tag DFS Item

This recombinant protein was expressed from a DNA sequence encoding the extracellular domain (Met 1-Thr 652) of human ERBB2 (NP_004439.2) fused to the Fc region of human IgG1 at the C-terminus

Manufacturer: life technologies  LS10004H02H50

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For Research Use Only. Not for use in diagnostic procedures.

Catalog No. 10004H02H50


Description & Specifications


For Use With (Application) Proteins, Expression, Isolation & Analysis; Enzyme & Protein Activity Assays; Protein Assay Controls, Reference Standards & Accessories
Format Lyophilized
Molecular Weight 96.1kDa
Purity ≥85% by SDS-PAGE
Quantity 50μg
Storage Requirements Store at -20°C. Store aliquots under sterile conditions at -20°C. Avoid repeated freeze-thaw cycles. Expires one year from date of receipt when stored as instructed.
Structural Form Truncated/Recombinant/Cell Surface Protein
Protein Subtype Receptor Tyrosine Kinases|Growth Factor Receptors
Endotoxin Concentration <1 EU/μg
Gene Alias ErbB2, NEU, NGL, HER2, TKR1, CD340, HER-2, c-erb B2, HER-2/neu
Common Name v-erb-b2 erythroblastic leukemia viral oncogene homolog 2
Gene Symbol ERBB2
Protein Tag IgG1 Fc Tag
Validated Application Assay Standard
Protein Family Growth Factors & Receptors
Expression System Mammalian
KinaseFamily EGF Receptor (ErbB) Kinase Family

V-erb-b2 erythroblastic leukemia viral oncogene homolog 2 (ERBB2), recombinant human protein is supplied as a lyophilized powder. In general, recombinant proteins are suitable for use in studying protein-protein interactions, as a protein standard, or in cell biology research applications. Since this product is a truncated protein and does not contain intracellular catalytic activity domain, it is not suitable for use in enzyme activity studies.

  • Activity: Measured by its binding ability in a functional ELISA; immobilized human ERBB2 at 2.5μg/mL can bind Herceptin with a linear range of 3.2-80ng/mL
  • Formulation: Lyophilized in 140mM NaCl, 2.7mM KCl, 10mM Na2HPO4, 1.8mM KH2PO4, pH 7.4, 5% Mannitol, 5% Trehalose, 0.02% Tween-80
  • Reconstitution: Dissolve the protein in sterile double distilled water to a concentration of 0.2mg/mL or lower; aliquot and use as soon as possible

This protein is manufactured by Sino Biological Inc.