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Sino Biological™ CD63 Recombinant Human Protein, His Tag DFS Item

This recombinant human protein is expressed from a DNA sequence encoding the second the extracellular domain (Ala 103-Val 203) of human CD63 (P08962-1) fused to both a polyhistidine tag at the C-terminus and a signal peptide at the N-terminus

Manufacturer: life technologies  LS11271H08H250

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For Research Use Only. Not for use in diagnostic procedures.

Catalog No. 11271H08HL


Description & Specifications


For Use With (Application) Proteins, Expression, Isolation & Analysis; Enzyme & Protein Activity Assays; Protein Assay Controls, Reference Standards & Accessories
Format Lyophilized
Gene ID (Entrez) 967
Molecular Weight 13kDa
Purity ≥90% by SDS-PAGE
Quantity 5 x 50μg
Storage Requirements Store at -20° to -70°C. Store aliquots under sterile conditions at -20°C. Avoid repeated freeze-thaw cycles. Expires one year from date of receipt when stored as instructed.
Structural Form Truncated/Recombinant/Cell Surface Protein
Protein Subtype Glycoproteins
Endotoxin Concentration <1 EU/μg
Gene Alias LAMP-3, ME491, MLA1, OMA81H, TSPAN30
Common Name CD63 molecule
Gene Symbol CD63
Protein Tag His Tag
Validated Application Assay Standard
Protein Family CD Proteins
Expression System Mammalian

Cluster of Differentiation 63 (CD63) recombinant human protein is supplied as a lyophilized powder. This protein is suitable for use in analysis of protein structure. In general, recombinant proteins can also be used as an immunogen, as a protein standard, or in cell biology research applications.&line-break;Background: CD63, is a multipass membrane protein which belongs to the tetraspanin (TM4SF) family. Tetraspanins participate in a variety of cellular processes, like cell activation, adhesion, differentiation and tumour invasion. CD63/Tspan-30 is expressed in melanoma and appears to be involved in regulation of motility and adhesion of melanoma cells. CD63/Tspan-30 is associated with early stages of melanoma tumor progression. It may play a role in growth regulation. Lack of expression of CD63 in platelets has been observed in a patient with Hermansky-Pudlak syndrome (HPS), which is a genetically heterogeneous, rare, autosomal recessive disorder characterized by oculocutaneous albinism, bleeding due to platelet storage pool deficiency, and lysosomal storage defects.

  • Activity: This recombinant protein has not been tested
  • Formulation: lyophilized in PBS, pH 7.4, 5% mannitol, 5% trehalose, and 0.02% Tween®-80
  • Reconstitution: Dissolve the protein in sterile double-distilled water to a concentration of 0.2mg/mL or lower; aliquot and use as soon as possible

Shipping Condition: Room Temperature. Manufactured by Sino Biological (China).