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CD19 Recombinant Human Protein, His Tag, Invitrogen™ Sino Biological™ DFS Item

This recombinant protein is expressed from a DNA sequence encoding the extracellular domain (Met 1-Lys 291) of human CD19 (AAB60697) fused to a polyhistidine tag at the C-terminus

$171.00 - $2,370.00

Specifications

Purity ≥90% by SDS-PAGE
Endotoxin Concentration <1 EU/μg
Format Lyophilized
Gene Alias B4, mgC12802
Gene ID (Entrez) 930
View More Specs

Products 4
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
11880H08H5 View Documents Life Technologies
LS11880H08H5
5μg Each for $171.00
 
11880H08H25 View Documents Life Technologies
LS11880H08H25
5 x 5μg Each for $449.00
 
11880H08H50 View Documents Life Technologies
LS11880H08H50
50μg Each for $744.00
 
11880H08HL View Documents Life Technologies
LS11880H08H250
5 x 50μg Each for $2,370.00
 
Description

Description

Cluster of Differentiation 19 (CD19) recombinant human protein is supplied as a lyophilized powder. This protein is suitable for use in analysis of protein structure the study of protein-protein interactions, and cell biology research applications. It can also be used as an immunogen, or as a protein standard.
Background: Cluster of Differentiation 19 (CD19), is a single-pass type I membrane protein which contains two Ig-like C2-type (immunoglobulinlike) domains. CD19 forms a complex with CD21, CD81 and CD225 in the membrane of mature B cells. It interacts with VAV. It interacts with GRB2 and SOS when phosphorylated on Tyr-348 and/or Tyr-378. CD19 also interacts with PLCG2 when phosphorylated on Tyr-409. CD19 is an important pan B cell marker and co-stimulatory protein in humans and mice. CD19 is a hallmark differentiation antigen of the B cell lineage and positively regulates antigen receptor signal transduction in mature B cells. CD19 defines signaling thresholds for the Ag receptor as well as other cell surface receptors that regulate B lymphocyte selection, activation, and differentiation. Defects in CD19 are a cause of hypogammaglobulinemia.
  • N-terminal Sequence Analysis: Pro 20
  • Activity: Measured by its binding ability in a functional ELISA; immobilized human CD19 at 2μg/mL (100μL/well) has been shown to bind biotinylated human CD9 with a linear range of 0.032-0.8μg/mL
  • Formulation: lyophilized in PBS, pH 7.4, 5% mannitol, 5% trehalose, and 0.02% Tween™-80
  • Reconstitution: Dissolve the protein in sterile double-distilled water to a concentration of 0.2mg/mL or lower; aliquot and use as soon as possible

Shipping Condition: Room Temperature. Manufactured by Sino Biological (China).

Specifications

Specifications

≥90% by SDS-PAGE
Lyophilized
930
<1 EU/μg
B4, mgC12802

For Research Use Only. Not for use in diagnostic procedures.