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Sino Biological™ BMPR1A, Recombinant Human Protein (without Catalytic Activity Domain), hIgG1-Fc.His Tag DFS Item


This recombinant protein was expressed from a DNA sequence encoding the extracellular domain (Met 1-Arg 152) of human ALK3 (NP_004320.2) fused to the C-terminal polyhistidine-tagged Fc region of human IgG1 at the C-terminus

Manufacturer: life technologies  LS10446H03H50

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 Disclaimers

For Research Use Only. Not for use in diagnostic procedures.

Catalog No. 10446H03H50

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Description & Specifications

Specifications

For Use With (Application) Proteins, Expression, Isolation & Analysis; Enzyme & Protein Activity Assays; Protein Assay Controls, Reference Standards & Accessories
Gene ID (Entrez) 657
Molecular Weight 42kDa
Purification Method PAGE
Purity ≥85% by SDS-PAGE
Quantity 50μg
Storage Requirements Store at -5° to -30°C. Store aliquots under sterile conditions at -20°C. Avoid repeated freeze-thaw cycles. Expires one year from date of receipt when stored as instructed.
Structural Form Truncated/Recombinant
Endotoxin Concentration <1 EU/μg
Gene Alias ACVRLK3, ALK3, CD292, BMPR1A
Common Name Bone morphogenetic protein receptor, type IA
Gene Symbol BMPR1A
Protein Tag hIgG1-Fc His
Validated Application Assay Standard
Protein Family Growth Factors & Receptors
Expression System Mammalian

Bone Morphogenetic Protein Receptor, Type IA (BMPR1A), recombinant human protein is supplied as a lyophilized powder. It is suitable for use in analysis of protein structure, and performing cell based assays. It can also be used as an immunogen, as a protein standard, or in other research applications. Since this product is a truncated protein and does not contain intracellular catalytic activity domain, it is not suitable for use in enzyme activity studies.

  • Activity: Measured by its ability to inhibit BMP4 induced activity in MC3T3-E1 Mouse osteoblastic cells, the ED50 for this effect is typically 0.1-0.3μg/mL in the presence of 50ng/mL of recombinant human BMP4
  • Formulation: 140mM NaCl, 2.7mM KCl, 10mM Na2HPO4, 1.8mM KH2PO4, pH 7.4, 5% Mannitol, 5% Trehalose, 0.02% Tween 80
  • Reconstitution: Dissolve the protein in sterile double distilled water to a concentration of 0.2mg/mL or lower; aliquot and use as soon as possible

This protein is manufactured by Sino Biological Inc.