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Sino Biological™ BACE1 Recombinant Human Protein, hIgG1-Fc Tag DFS Item

This recombinant protein was expressed as a secreted protein from a DNA sequence encoding the extracellular domain (Met 1-Thr 457) of human BACE1 (NP_036236.1) fused to the Fc region of human IgG1 at the C-terminus

Manufacturer: life technologies  LS10064H02H25

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For Research Use Only. Not for use in diagnostic procedures.

Catalog No. 10064H02H25


Description & Specifications


For Use With (Application) Proteins, Expression, Isolation & Analysis; Enzyme & Protein Activity Assays; Protein Assay Controls, Reference Standards & Accessories
Format Lyophilized
Gene ID (Entrez) 23621
Molecular Weight 75kDa
Purity ≥85% by SDS-PAGE
Quantity 5 x 5μg
Storage Requirements Store at -20° to -70°C. Store aliquots under sterile conditions at -20°C. Avoid repeated freeze-thaw cycles. Expires one year from date of receipt when stored as instructed.
Structural Form Truncated/Recombinant
Protein Subtype Proteases
Endotoxin Concentration <1 EU/μg
Gene Alias BACE1, ASP2, BACE, HSPC104, FLJ90568, KIAA1149
Common Name beta-site APP-cleaving enzyme 1
Gene Symbol BACE1
Protein Tag IgG1 Fc Tag
Validated Application Assay Standard
Protein Family Other Proteins
Expression System Mammalian

Beta-secretase 1, recombinant human protein is supplied as a lyophilized powder. It is suitable for use in performing enzymatic assays, and cell biology research applications. It can also be used as a protein standard.

  • Activity: Measured by its ability to cleave a fluorogenic peptide substrate, Mca-SEVNLDAEFRK(Dpn)RR-NH2; the specific activity is >0.5 pmoles/min./μg
  • Formulation: Lyophilized in PBS, pH 7.4, 5% Mannitol, 5% Trehalose, and 0.02% Tween 80
  • Reconstitution: Dissolve the protein in sterile double distilled water to a concentration of 0.2mg/mL or lower; aliquot and use as soon as possible

Shipping Condition: Room Temperature. This protein is manufactured by Sino Biological Inc.