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Invitrogen™ SIK1 Recombinant Human Protein DFS Item

SIK1 is a protein kinase that is involved in regulating AMPK-related kinases. This recombinant human SIK1 (1-303) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

$594.00 - $9,080.00

Specifications

Host Species Human
Protein Tag GST Tag
Recombinant Yes
View More Specs

Products 3
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
PV6445 View Documents Invitrogen™
LSPV6445
10μg Each for $594.00
 
PV6447 View Documents Invitrogen™
LSPV6447
1mg Each for $9,080.00
 
PV6446 View Documents Invitrogen™
LSPV6446
100μg Each for $2,030.00
 
Description

Description

  • Validated in LanthaScreen™ Kinase Binding Assay
  • Protocols available for simple use and optimized performance

SIK1 may mediate the physiological effects of LKB1, including its tumour suppressor function. SIK1 is also involved in signaling by various proteins like STRAD, NUAK1, NUAK2, BRSK1, BRSK2, QIK, QSK, SIK, MARK1, MARK2, MARK3, MARK4, and MELK that are related to AMPK. Activation of SIK1 by phosphorylation on thr322 can lead to an increase in the catalytic activity of sodium/potassium ATPase alpha subunit at the plasma membrane. This results in an increase in intracellular sodium in intact mammalian cells.

Specifications

Specifications

Human
GST Tag
Yes