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Tocris™ SIB 1893

mGlu5 antagonist and positive allosteric modulator at mGlu4

$168.15 - $697.40

Specifications

Product Type SIB 1893
Inhibitors SIB 1893
Molecular Weight 195.26
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Disclaimers:

For Research Use Only



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
1214/10 Tocris™
121410
10mg Each for $168.15
121450R Tocris™
121450
50mg Each for $697.40
Specifications

Description

A highly selective non-competitive antagonist for the metabotropic glutamate mGlu5 receptor subtype; displays an IC50 value of 0.3μM at hmGlu5, compared with > 100μM at hmGlu1b, hmGlu2, hmGlu6, hmGlu7 and hmGlu8. Centrally active upon systemic administration in vivo. Positive allosteric modulator at mGlu4 receptors.
  • Chemical Name: 2-Methyl-6-(2-phenylethenyl)pyridine
  • Formula: C14H13N
  • CAS Number: 6266-99-5
  • Solubility: Soluble to 100mM in DMSO
Description & Specifications

Specifications

SIB 1893
SIB 1893
195.26