Thermo Scientific™ Lab Vision™ SHP-1 Ab-1, Mouse Monoclonal Antibody
Provide accurate, reproducible results with the Thermo Scientific™ SHP-1 Ab-1, Mouse Monoclonal Antibody.
Manufacturer: Thermo Scientific™ Lab Vision™ MS1190P1ABX
Provide accurate, reproducible results with the Thermo Scientific™ SHP-1 Ab-1, Mouse Monoclonal Antibody.Shp-1 is a SH2-containing protein-tyrosine phosphatase 1 (SHP-1). SHP-1 is known to play a crucial role in the regulation of hematopoiesis and it regulates the transcriptional activity stimulated by the erythropoietin (EPO)-induced JAK/STAT and MAPK pathways and is involved in the signaling machinery responsible for erythroid differentiation and suppression of apoptosis. Furthermore, the observation that SHP-1 associates with RAFTK/Pyk2/CAK activated by β-chemokine receptor (CCR5) and SHP-1 also associates with the adaptor protein Grb2 and the Src-related kinase Syk indicates the role of SHP-1 in modulating cell migration, proliferation, and immune functions.
Host Species: Mouse
Clone: 1SH01; same as 11D7C8H5
Species Reactivity: Human. Others not known.
Epitope: Not determined
Immunogen: Recombinant human SHP-1 protein
Molecular Weight: ∽68kDa
Positive Control: Jurkat or HeLa cells
Cellular Localization: Cytoplasmic
- Western Blotting
- Immunoprecipitation (Not verified)
USA: RUO; Int'l: RUO
|1SH01; same as 11D7C8H5|
|Recombinant human SHP1 protein|