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Semaphorin 4A Mouse anti-Human, Mouse, PerCP-eFluor 710, Clone: 5E3, eBioscience™

Mouse Monoclonal Antibody

$201.55 - $477.05

Specifications

Antigen Semaphorin 4A
Clone 5.00E+03
Host Species Mouse
Gene Alias Sema B, Sema4A
Species Reactivity Human, Mouse
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 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

501123961

 
affymetrix
46975341
25 tests Each for $201.55

501123962

 
affymetrix
46975342
100 tests Each for $477.05
Description & Specifications

Specifications

Antigen Semaphorin 4A
Clone 5.00E+03
Host Species Mouse
Gene Alias Sema B, Sema4A
Species Reactivity Human, Mouse
Applications Flow Cytometry
Regulatory Status RUO
Conjugate PerCP-eFluor 710
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material. This tandem dye is sensitive to photo-induced oxidation. Protect this vial from light during storage
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 5μL (0.06μg)/test

The monoclonal antibody 5E3 reacts with human and mouse Semaphorin 4A (Sema4A). This 150kDa glycoprotein is a member of the class IV semaphorin family and exists as membrane-bound and soluble forms. Sema4A is expressed by a wide variety of tissues, including lung, kidney, spleen, testis, and mammary glands, as well as activated T cells and dendritic cells. This ligand binds to Tim-2, neuropilin-1 (Nrp1), plexin D1, and plexin B1. Sema4A plays a role in T cell activation, Th1 differentiation, and Treg function and survival.

Our testing demonstrates that the 5E3 antibody stains resting CD49b+ NK cells in mouse. However, staining of CD56+ NK cells in human is negative.