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Tocris™ SB 657510

Selective urotensin-II (UT) receptor antagonist

$242.90 - $1,021.74

Specifications

Product Type SB 657510
Inhibitors SB 657510
Molecular Weight 505.81
Purity >98
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 Disclaimers

For Research Use Only

Products
Catalog Number Mfr. No. Quantity Price Quantity    

357110R

 
tocris™
3571/10
10mg Each for $242.90

357150R

 
tocris™
3571/50
50mg Each for $1,021.74
Description & Specifications

Specifications

Product Type SB 657510
Inhibitors SB 657510
Molecular Weight 505.81
Purity >98

Selective urotensin-II (UT) receptor antagonist (Ki values are 61, 17, 30, 65 and 56nM at human, monkey, cat, rat and mouse receptors respectively). Inhibits U-II-induced intracellular Ca2+ mobilization (IC50 = 180nM) and antagonizes the contractile action of U-II in isolated mammalian arteries and aortae (EC50 = 50 - 189nM).

  • Chemical Name: 2-Bromo-N-[4-chloro-3-[[(3R)-1-methyl-3-pyrrolidinyl]oxy]phenyl]-4,5-dimethoxybenzenesulfonamide
  • Formula: C19H22BrClN2O5S
  • CAS Number: 474960-44-6
  • Solubility: Soluble to 100mM in DMSO
  • Purity: >98