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Tocris™ SB 612111 hydrochloride

Selective NOP receptor antagonist

$307.17 - $1,291.63

Specifications

Product Type SB 612111 hydrochloride
Inhibitors SB 612111 hydrochloride
Molecular Weight 454.86
Purity >98
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 Disclaimers

For Research Use Only

Products
Catalog Number Mfr. No. Quantity Price Quantity    

357310R

 
tocris™
3573/10
10mg Each for $307.17

357350R

 
tocris™
3573/50
50mg Each for $1,291.63
Description & Specifications

Specifications

Product Type SB 612111 hydrochloride
Inhibitors SB 612111 hydrochloride
Molecular Weight 454.86
Purity >98

Selective NOP receptor antagonist (Ki values are 0.33, 57.6, 160.5 and 2109nM for NOP,μ-, κ- and δ-receptors respectively). Antagonizes the pronociceptive action of nociceptin (Cat. No. 0910) in an acute pain model. Potentiates the action of morphine in morphine-tolerant animals and blocks hyperalgesia in an inflammatory pain model.

  • Chemical Name: 7-[[4-(2,6-Dichlorophenyl)-1-piperidinyl]methyl]-6,7,8,9-tetrahydro-1-methyl-5H-benzocyclohepten-5-ol hydrochloride
  • Formula: C24H29Cl2NO.HCl
  • CAS Number: 371980-94-8
  • Solubility: Soluble to 100mM in DMSO and to 100mM in ethanol
  • Purity: >98