missing translation for 'onlineSavingsMsg'
Learn More
Please login to your online account to display your discounted pricing

Tocris™ SB 525334

Selective inhibitor of TGF-betaRI

$257.85 - $1,073.10

Specifications

Product Type SB 525334
Inhibitors SB 525334
Molecular Weight 343.42
Purity >97
View More Specs

Disclaimers:

For Research Use Only



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
321110 Tocris™
321110
10mg Each for $257.85
321150 Tocris™
321150
50mg Each for $1,073.10
Specifications

Description

Selective inhibitor of transforming growth factor-β receptor I (ALK5, TGF-βRI) (IC50 = 14.3nM). Inhibits TGF-β1-induced smad2/3 nuclear localization and TGF-βRI-induced mRNA expression in kidney cells. Attenuates bleomycin-induced pulmonary fibrosis.
  • Chemical Name: 6-[2-(1,1-Dimethylethyl)-5-(6-methyl-2-pyridinyl)-1H-imidazol-4-yl]quinoxaline
  • Formula: C21H21N5
  • CAS Number: 356559-20-1
  • Solubility: Soluble to 100mM in DMSO and to 100mM in 1eq. HCl
  • Purity: >97
Description & Specifications

Specifications

SB 525334
SB 525334
343.42
>97