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Tocris™ SB 328437

Potent and selective CCR3 antagonist

$212.06 - $893.21

Specifications

Product Type SB 328437
Inhibitors SB 328437
Molecular Weight 378.38
Purity >99
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 Disclaimers

For Research Use Only

Products
Catalog Number Mfr. No. Quantity Price Quantity    

365010R

 
tocris™
3650/10
10mg Each for $212.06

365050R

 
tocris™
3650/50
50mg Each for $893.21
Description & Specifications

Specifications

Product Type SB 328437
Inhibitors SB 328437
Molecular Weight 378.38
Purity >99

Potent and selective CCR3 antagonist (IC50 = 4nM). Displays > 2500-fold selectivity over C5aR, LTD4, CCR7, CXCR1 and CXCR2 receptors. Inhibits eotaxin-, eotaxin-2- and MCP-4-induced Ca2+ mobilization (IC50 values are 38, 35 and 20nM respectively) and inhibits eotaxin-, eotaxin-2- and MCP-4-induced eosinophil chemotaxis with similar potencies.

  • Chemical Name: N-(1-Naphthalenylcarbonyl)-4-nitro-L-phenylalanine methyl ester
  • Formula: C21H18N2O5
  • CAS Number: 247580-43-4
  • Solubility: Soluble to 100mM in DMSO
  • Purity: >99