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Tocris™ SANT-2

Inhibitor of Hedgehog (Hh) signaling; antagonizes smoothened activity

$230.05 - $957.48

Specifications

Product Type SANT-2
Inhibitors SANT-2
Molecular Weight 479.96
Purity >98
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 Disclaimers

For Research Use Only

Products
Catalog Number Mfr. No. Quantity Price Quantity    

361710R

 
tocris™
3617/10
10mg Each for $230.05

361750R

 
tocris™
3617/50
50mg Each for $957.48
Description & Specifications

Specifications

Product Type SANT-2
Inhibitors SANT-2
Molecular Weight 479.96
Purity >98

Inhibitor of Sonic hedgehog (Shh) signaling; antagonizes smoothened receptor activity (KD = 12nM). Displays allosteric binding characteristics similar to SANT-1 (Cat. No. 1974). Displaces smo-[3H]SAG-1.3 and -[3H]Cyclopamine binding (Ki values are 7.8nM and 8.4nM respectively).

  • Chemical Name: N-[3-(1H-Benzimidazol-2-yl)-4-chlorophenyl]-3,4,5-triethoxybenzamide
  • Formula: C26H26ClN3O4
  • CAS Number: 329196-48-7
  • Solubility: Soluble to 100mM in DMSO and to 100mM in ethanol
  • Purity: >98