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Runx3 Mouse anti-Human, Clone: R3-5G4, eBioscience™

Mouse Monoclonal Antibody

$129.05 - $317.55

Specifications

Antigen Runx3
Clone R3-5G4
Host Species Mouse
Gene Alias AML2, CBFA3
Species Reactivity Human
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

501122880

 
affymetrix
14981780
25μg Each for $129.05

501122881

 
affymetrix
14981782
100μg Each for $317.55
Description & Specifications

Specifications

Antigen Runx3
Clone R3-5G4
Host Species Mouse
Gene Alias AML2, CBFA3
Species Reactivity Human
Applications Immunohistochemistry
Applications Immunohistochemistry (Formalin/Paraffin)
Applications Western Blotting
Regulatory Status RUO
Conjugate Unlabeled
Format Purified
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.5mg/mL

This R3-5G4 monoclonal antibody recognizes human Runx3, a 44kDa transcription factor that belongs to the Runt domain-containing family. Runx3 is expressed in hematopoietic cells such as T cells, B cells, and myeloid cells. This transcription factor is also expressed in non-hematopoietic tissues, including the epidermis, bone, and dorsal root ganglia. Runx3 has been established to play a critical role in thymocyte development. More specifically, Runx3 promotes CD8 + T cell development by silencing Cd4 expression. Finally, studies have demonstrated the tumor suppressive activity of in a variety of cancers (e.g., gastric and breast cancers).