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Thermo Scientific™ Lab Vision™ RPA/p70 (Replication Protein A) Ab-2, Mouse Monoclonal Antibody


Provide accurate, reproducible results Thermo Scientific™ RPA/p70 (Replication Protein A) Ab-2, Mouse Monoclonal Antibody.

Manufacturer: thermo scientific™ lab vision™  MS692P1ABX

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Catalog No. MS692P1ABX

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Description & Specifications

Specifications

Antigen RPA/p70 (Replication Protein A) Ab-2
Applications Immunoprecipitation
Applications Western Blotting
Classification Monoclonal
Clone 2H10 or 70C or alphaSSB70C
Concentration 1mg/mL
Conjugate Unlabeled
Cross Reactivity Human
Format Concentrated
Host Species Mouse
Immunogen Purified human RPA protein
Isotype IgG2a kappa
Quantity 100µL
Regulatory Status RUO
Research Discipline DNA Repair
Type Primary

Provide accurate, reproducible results Thermo Scientific™ RPA/p70 (Replication Protein A) Ab-2, Mouse Monoclonal Antibody.

Replication Protein A (RPA) (also known as human single-stranded DNA binding protein, or HSSB) is involved in DNA replication, repair, and recombination. RPA from human cells is a stable heterotrimer of 70kDa, 32-34kDa, and 11-14kDa subunits (RPA70, RPA32, and RPA14 respectively). RPA is required for the SV40 large tumor antigen-catalyzed unwinding of SV40 DNA and stimulates DNA polymerase α and δ. RPA70 is composed of three domains: an N-terminal domain that is not required for ssDNA binding or SV40 replication, a central DNA-binding domain, and a C-terminal domain that is essential for subunit interactions.

Host Species: Mouse

Clone: 2H10 or 70C or αSSB70C

Isotype: IgG1/κ

Species Reactivity: Human. Others not known.

Epitope: Not determined

Immunogen: Purified human RPA protein

Molecular Weight: 70kDa

Positive Control: HeLa cells

Cellular Localization: Nuclear

Recommended for:

  • Immunohistochemistry (Not suitable)
  • Western Blotting
  • Immunoprecipitation (Native and denatured)
  • Gel Supershift

Note:

USA: RUO; Int'l: RUO