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Thermo Scientific™ Lab Vision™ RPA/p70 (Replication Protein A) Ab-2, Mouse Monoclonal Antibody

Provide accurate, reproducible results Thermo Scientific™ RPA/p70 (Replication Protein A) Ab-2, Mouse Monoclonal Antibody.

Manufacturer:  Thermo Scientific™ Lab Vision™ MS692P1ABX

 View more versions of this product

Catalog No. MS692P1ABX


 

Specifications

Description

Provide accurate, reproducible results Thermo Scientific™ RPA/p70 (Replication Protein A) Ab-2, Mouse Monoclonal Antibody.

Replication Protein A (RPA) (also known as human single-stranded DNA binding protein, or HSSB) is involved in DNA replication, repair, and recombination. RPA from human cells is a stable heterotrimer of 70kDa, 32-34kDa, and 11-14kDa subunits (RPA70, RPA32, and RPA14 respectively). RPA is required for the SV40 large tumor antigen-catalyzed unwinding of SV40 DNA and stimulates DNA polymerase α and δ. RPA70 is composed of three domains: an N-terminal domain that is not required for ssDNA binding or SV40 replication, a central DNA-binding domain, and a C-terminal domain that is essential for subunit interactions.

Host Species: Mouse

Clone: 2H10 or 70C or αSSB70C

Isotype: IgG1/κ

Species Reactivity: Human. Others not known.

Epitope: Not determined

Immunogen: Purified human RPA protein

Molecular Weight: 70kDa

Positive Control: HeLa cells

Cellular Localization: Nuclear

Recommended for:

  • Immunohistochemistry (Not suitable)
  • Western Blotting
  • Immunoprecipitation (Native and denatured)
  • Gel Supershift

Note:

USA: RUO; Int'l: RUO

Description & Specifications

Specifications

RPA/p70 (Replication Protein A) Ab-2
Monoclonal
1mg/mL
Concentrated
Purified human RPA protein
100μL
DNA Repair
Monoclonal
Immunoprecipitation,Western Blotting
2H10 or 70C or alphaSSB70C
Unlabeled
Murine
IgG2a kappa
RUO
Primary
Human