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ROR gamma (t) Rat anti-Mouse, PE-eFluor 610, Clone: B2D, eBioscience™

Rat Monoclonal Antibody

$259.55 - $665.55

Specifications

Antigen ROR gamma (t)
Clone B2D
Host Species Rat
Gene Alias Retinoid-Related Orphan Receptor gamma
Species Reactivity Mouse
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

501124862

 
affymetrix
61698180
25μg Each for $259.55

501124863

 
affymetrix
61698182
100μg Each for $665.55
Description & Specifications

Specifications

Antigen ROR gamma (t)
Clone B2D
Host Species Rat
Gene Alias Retinoid-Related Orphan Receptor gamma
Species Reactivity Mouse
Applications Flow Cytometry (Intracellular Staining)
Regulatory Status RUO
Conjugate PE-eFluor 610
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material. This tandem dye is sensitive to photo-induced oxidation. Protect this vial from light during storage
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.2mg/mL

The B2D monoclonal antibody reacts with the mouse ROR gamma (t) protein. ROR gamma is a member of the retinoic acid-related orphan receptor (ROR) family, which also includes ROR alpha and ROR beta. ROR family proteins are ligand-dependent transcription factors that play roles in multiple physiological processes. ROR gamma is expressed in several tissues including liver, lung, muscle, heart and kidney. Furthermore, it was discovered that alternative transcription results in the expression of an isoform, ROR gamma t, which is expressed exclusively in cells of the lymphoid compartment, namely CD4+CD8+ “double-positive” thymoyctes, Th17 cells of the periphery and lymphoid tissue inducer (Lti) cells of lymphoid organs.

The ROR gamma t isoform differs from ROR gamma by three unique amino acids at the amino terminus. Therefore, the B2D antibody will react with both the ROR gamma and ROR gamma t isoforms.