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ROR gamma (t) Rat anti-Mouse, Clone: B2D, eBioscience™

Rat Monoclonal Antibody

$216.05 - $506.05

Specifications

Antigen ROR gamma (t)
Clone B2D
Host Species Rat
Gene Alias RORgamma, RORg, RORg(t), Retinoid-Related Orphan Receptor gamma
Species Reactivity Mouse
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5013562

 
affymetrix
14698180
25μg Each for $216.05

5013563

 
affymetrix
14698182
100μg Each for $506.05
Description & Specifications

Specifications

Antigen ROR gamma (t)
Clone B2D
Host Species Rat
Gene Alias RORgamma, RORg, RORg(t), Retinoid-Related Orphan Receptor gamma
Species Reactivity Mouse
Applications Western Blotting
Regulatory Status RUO
Conjugate Unlabeled
Format Purified
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.5mg/mL

The B2D monoclonal antibody reacts with the mouse RORγ(t) protein. RORγ is a member of the retinoic acid-related orphan receptor (ROR) family, which also includes RORα and RORβ. ROR family proteins are ligand-dependent transcription factors that play roles in multiple physiological processes. RORγ is expressed in several tissues including liver, lung, muscle, heart and kidney. Furthermore, it was discovered that alternative transcription results in the expression of an isoform, RORγt, which is expressed exclusively in cells of the lymphoid compartment, namely CD4+CD8+ “double-positive” thymoyctes, Th17 cells of the periphery and lymphoid tissue inducer (Lti) cells of lymphoid organs.

The RORγt isoform differs from RORγ by three unique amino acids at the amino terminus. Therefore, the B2D antibody will react with both the RORγ and RORγt isoforms.