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Thermo Scientific™ Lab Vision™ ROC1 Ab-1, Rabbit Polyclonal Antibody

Provide accurate, reproducible results with the Thermo Scientific™ ROC1 Ab-1, Rabbit Polyclonal Antibody.

$254.86 - $1,287.02

Specifications

Antigen ROC1 Ab-1
Concentration 1mg/mL
Applications Western Blotting
Classification Polyclonal
Conjugate Unlabeled
View More Specs
Products
Catalog Number Mfr. No. Formulation Quantity Price Quantity    

RB069P

 
thermo scientific™ lab vision™
RB-069-P
Purified Ab with BSA and Azide 1mL Each for $1,193.90

RB069P0

 
thermo scientific™ lab vision™
RB-069-P0
Purified Ab with BSA and Azide 100µL Each for $254.86

RB069P1

 
thermo scientific™ lab vision™
RB-069-P1
Purified Ab with BSA and Azide 500µL Each for $722.57

RB069P1ABX

 
thermo scientific™ lab vision™
RB069P1ABX
Ab without BSA/Azide (Frozen) 500µL Each for $789.02

RB069PABX

 
thermo scientific™ lab vision™
RB-069-PABX
Ab without BSA/Azide (Frozen) 1mL Each for $1,287.02
Description & Specifications

Specifications

Antigen ROC1 Ab-1
Concentration 1mg/mL
Applications Western Blotting
Classification Polyclonal
Conjugate Unlabeled
Cross Reactivity Human
Format Concentrated
Host Species Rabbit
Regulatory Status RUO
Research Discipline Cell Cycle
Type Primary
Immunogen A peptide corresponding to amino acid residue 97-108 (CPLDNREWEFQKYGH) from C-terminus of the human ROC1
Isotype IgG

Provide accurate, reproducible results with the Thermo Scientific™ ROC1 Ab-1, Rabbit Polyclonal Antibody.

ROC1 and ROC2 are the two highly conserved RING finger proteins that are homologous to APC11, a subunit of the anaphase-promoting complex(APC). ROC1 and ROC2 commonly interact with all cullins while APC11 specifically interacts with APC2, a cullin-related APC subunit. ROC1 and APC11 immunocomplexes can catalyze isopeptide ligations to form polyubiquitin chains in an E1- and E2-dependent manner. ROC1 is thought to play a unique role in the ubiquitination reaction by heterodimerizing with cullin1 to catalyze ubiquitin polymerization.

Host Species: Rabbit

Isotype: IgG

Species Reactivity: Human and Mouse. Others not known.

Epitope: aa 97-108

Immunogen: A peptide corresponding to amino acid residue 97-108 (CPLDNREWEFQKYGH) from C-terminus of the human ROC1

Molecular Weight: 13kDa

Positive Control: HeLa cells

Cellular Localization: Nuclear

Recommended for:

  • Western Blotting
  • Immunoprecipitation (Native verified)
General References:

1. Tan P, et al. Mol Cell 1999 Apr 3 (4): 527.

2. Skowyra D, et al. Science 1999. 284 (5414): 662.

3. Ohta T, et al. Mol Cell 1999 Apr 3(4): 535.