Thermo Scientific™ Lab Vision™ ROC1 Ab-1, Rabbit Polyclonal Antibody
Provide accurate, reproducible results with the Thermo Scientific™ ROC1 Ab-1, Rabbit Polyclonal Antibody.
Manufacturer: Thermo Scientific™ Lab Vision™ RB069P1ABX
Provide accurate, reproducible results with the Thermo Scientific™ ROC1 Ab-1, Rabbit Polyclonal Antibody.ROC1 and ROC2 are the two highly conserved RING finger proteins that are homologous to APC11, a subunit of the anaphase-promoting complex(APC). ROC1 and ROC2 commonly interact with all cullins while APC11 specifically interacts with APC2, a cullin-related APC subunit. ROC1 and APC11 immunocomplexes can catalyze isopeptide ligations to form polyubiquitin chains in an E1- and E2-dependent manner. ROC1 is thought to play a unique role in the ubiquitination reaction by heterodimerizing with cullin1 to catalyze ubiquitin polymerization.
Host Species: Rabbit
Species Reactivity: Human and Mouse. Others not known.
Epitope: aa 97-108
Immunogen: A peptide corresponding to amino acid residue 97-108 (CPLDNREWEFQKYGH) from C-terminus of the human ROC1
Molecular Weight: 13kDa
Positive Control: HeLa cells
Cellular Localization: Nuclear
- Western Blotting
- Immunoprecipitation (Native verified)
USA: RUO; Int'l: RUO
|Ab without BSA/Azide (Frozen)|
|A peptide corresponding to amino acid residue 97-108 (CPLDNREWEFQKYGH) from C-terminus of the human ROC1|