Please login to your online account to display your discounted pricing

Thermo Scientific™ Lab Vision™ Retinoblastoma (Rb) Ab-5, Mouse Monoclonal Antibody

Provide accurate, reproducible results with the Thermo Scientific™ Retinoblastoma (Rb) Ab-5, Mouse Monoclonal Antibody.

$227.96 - $1,025.71

Specifications

Antigen Retinoblastoma (Rb) Ab-5
Clone XZ133
Applications Immunofluorescence
Applications Immunoprecipitation
Classification Monoclonal
View More Specs
Products
Catalog Number Mfr. No. Concentration Quantity Price Quantity    

MS595P

 
thermo scientific™ lab vision™
MS-595-P
200�g/mL 1mL Each for $945.88

MS595P0

 
thermo scientific™ lab vision™
MS-595-P0
200�g/mL 100µL Each for $227.96

MS595P1

 
thermo scientific™ lab vision™
MS-595-P1
200�g/mL 500µL Each for $633.65

MS595P1ABX

 
thermo scientific™ lab vision™
MS595P1ABX
1mg/mL 100µL Each for $717.24

MS595PABX

 
thermo scientific™ lab vision™
MS-595-PABX
1mg/mL 200µL Each for $1,025.71
Description & Specifications

Specifications

Antigen Retinoblastoma (Rb) Ab-5
Clone XZ133
Applications Immunofluorescence
Applications Immunoprecipitation
Classification Monoclonal
Conjugate Unlabeled
Cross Reactivity Chicken
Cross Reactivity Human
Cross Reactivity Mouse
Cross Reactivity Chicken
Cross Reactivity Human
Cross Reactivity Mouse
Format Concentrated
Host Species Mouse
Regulatory Status RUO
Research Discipline Cancer and Tumor Biology
Type Primary
Immunogen Recombinant human Rb protein corresponding to amino acids 387-928
Isotype IgG1

Provide accurate, reproducible results with the Thermo Scientific™ Retinoblastoma (Rb) Ab-5, Mouse Monoclonal Antibody.

Rb is a tumor suppressor nuclear phosphoprotein capable of binding to DNA. It is phosphorylated on serine and threonine, but not on tyrosine residues. It forms a complex with SV40 large T antigen, adenovirus E1A, and human papilloma virus-16 E. Rb protein may act by regulating transcription and loss of its function leads to uncontrolled cell growth. Aberrations in the RB gene have been implicated in cancers of breast, colon, prostate, kidney, nasopharynx, and leukemia.

Host Species: Mouse

Clone: XZ133

Isotype: IgG1

Species Reactivity: Human, Mouse (strong) and Chicken (strong). Does not react with Xenopus. Others not known.

Epitope: aa 620-665

Immunogen: Recombinant human Rb protein corresponding to amino acids 387-928

Molecular Weight: 105kDa

Positive Control: Ls174T, HT29, HUVEC cells

Cellular Localization: Nuclear Ab-5 reacts with the hyperphosphorylated as well as the under phosphorylated form of the Rb protein.

Recommended for:

  • Immunohistochemistry (Not suitable)
  • Western Blotting (Not suitable)
  • Immunofluorescence
  • Immunoprecipitation (Denatured verified)

Note:

USA: RUO; Int'l: RUO