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Thermo Scientific™ Lab Vision™ Retinoblastoma (Rb) Ab-1, Mouse Monoclonal Antibody

Provide accurate, reproducible results with the Thermo Scientific™ Retinoblastoma (Rb) Ab-1, Mouse Monoclonal Antibody.

$229.16 - $1,384.22

Specifications

Antigen Retinoblastoma (Rb) Ab-1
Clone 1F8; same as Rb1
Applications Flow Cytometry
Applications Immunofluorescence
Applications Immunohistochemistry (Paraffin)
View More Specs
Products
Catalog Number Mfr. No. Formulation Quantity Price Quantity    

MS107B

 
thermo scientific™ lab vision™
MS-107-B
Biotinylated Ab with BSA and Azide 1mL Each for $1,384.22

MS107B0

 
thermo scientific™ lab vision™
MS-107-B0
Biotinylated Ab with BSA and Azide 100µL Each for $319.10

MS107B1

 
thermo scientific™ lab vision™
MS-107-B1
Biotinylated Ab with BSA and Azide 500µL Each for $865.59

MS107P

 
thermo scientific™ lab vision™
MS-107-P
Purified Ab with BSA and Azide 1mL Each for $1,081.47

MS107P0

 
thermo scientific™ lab vision™
MS-107-P0
Purified Ab with BSA and Azide 100µL Each for $229.16

MS107P1

 
thermo scientific™ lab vision™
MS-107-P1
Purified Ab with BSA and Azide 500µL Each for $677.80

MS107P1ABX

 
thermo scientific™ lab vision™
MS107P1ABX
Ab without BSA/Azide (Frozen) 100µL Each for $757.18

MS107PABX

 
thermo scientific™ lab vision™
MS-107-PABX
Ab without BSA/Azide (Frozen) 200µL Each for $1,146.53

MS107R7

 
thermo scientific™ lab vision™
MS-107-R7
Ready-to-use for IHC (UVLP) 7mL Each for $452.82
Description & Specifications

Specifications

Antigen Retinoblastoma (Rb) Ab-1
Clone 1F8; same as Rb1
Applications Flow Cytometry
Applications Immunofluorescence
Applications Immunohistochemistry (Paraffin)
Applications Immunoprecipitation
Applications Western Blotting
Applications Flow Cytometry
Applications Immunofluorescence
Applications Immunohistochemistry (Paraffin)
Applications Immunoprecipitation
Applications Western Blotting
Applications Flow Cytometry
Applications Immunofluorescence
Applications Immunohistochemistry (Paraffin)
Applications Immunoprecipitation
Applications Western Blotting
Applications Flow Cytometry
Applications Immunofluorescence
Applications Immunohistochemistry (Paraffin)
Applications Immunoprecipitation
Applications Western Blotting
Applications Flow Cytometry
Applications Immunofluorescence
Applications Immunohistochemistry (Paraffin)
Applications Immunoprecipitation
Applications Western Blotting
Classification Monoclonal
Cross Reactivity Human
Host Species Mouse
Regulatory Status RUO
Research Discipline Cancer and Tumor Biology
Type Primary
Immunogen Recombinant human Rb protein
Isotype IgG1

Provide accurate, reproducible results with the Thermo Scientific™ Retinoblastoma (Rb) Ab-1, Mouse Monoclonal Antibody.

Rb is a tumor suppressor nuclear phosphoprotein capable of binding to DNA. It is phosphorylated on serine and threonine, but not on tyrosine residues. It forms a complex with SV40 large T antigen, adenovirus E1A, and human papilloma virus-16 E. Rb protein may act by regulating transcription and loss of its function leads to uncontrolled cell growth. Aberrations in the RB gene have been implicated in cancers of breast, colon, prostate, kidney, nasopharynx, and leukemia.

Host Species: Mouse

Clone: 1F8; same as Rb1

Isotype: IgG1

Species Reactivity: Human. Does not react with mouse and rat. Others not known.

Epitope: aa 703-722

Immunogen: Recombinant human Rb protein

Molecular Weight: 105kDa

Positive Control: Ls174T, HT29, HUVEC cells; Normal colon, Breast CA and colon CA

Cellular Localization: Nuclear Ab-1 specifically stains the nuclei of BT-20 cells and primary human foreskin fibroblast (HFF) cells. It reacts with hyperphosphorylated and un (under) phosphorylated form of Rb protein. It shows no cross reaction with p107 and p130.

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunofluorescence
  • Immunoprecipitation (Native and denatured)
  • Flow Cytometry

Note:

USA: RUO; Int'l: RUO