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Rat anti-PD-L2/B7-DC/PDCD1LG2, Clone: TY25, Biotin, Novus Biologicals™

Manufacturer: novus biologicals canada  NBP14350405MG

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For Research Use Only

Catalog No. NBP1435045

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Description & Specifications


Applications Flow Cytometry
Quantity 0.5mg
Cross Reactivity Mouse
Isotype IgG2a
Antigen PD-L2/B7-DC/PDCD1LG2
Conjugate Biotin
Host Species Rat
Regulatory Status RUO
Format Purified
Monoclonal or Polyclonal Monoclonal
Formulation Phosphate buffer pH 7.2. Protein G purified.
Concentration 0.5mg/mL
Storage Requirements Store at 4°C. Do not freeze.
Purification Method Purified
Immunogen B7-DC transfected RAW264.7 cells.
Primary or Secondary Primary
Gene ID (Entrez) 80380
Clone TY25
Test Specificity NB100-65332 recognizes mouse CD273, a 42kD member of the B7 family, otherwise known as B7-dendritic cell (B7-DC), or programmed death ligand-2 (PD-L2). The expression of CD273 is restricted to a subpopulation of dendritic cells (DCs), and DCs and macrophages that have been stimulated with interferon gamma, GM-CSF or IL-4. CD273 has been identified as a ligand for PD-1(CD279), along with another B7 family member B7-H1 (CD274). Studies suggest that both CD273 and B7-H1 co-stimulate or inhibit T cell proliferation and cytokine production. Antibodies produced by clone TY25 are reported to block the binding of CD273 (B7-DC) to it's receptor.