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Rat anti-MHC Class II, Clone: M5/114.15.2, Novus Biologicals™


Manufacturer: novus biologicals canada  NBP14331205MG

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 Disclaimers

For Research Use Only

Catalog No. NBP1433125

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Description & Specifications

Specifications

Applications Flow Cytometry
Applications Functional Assay
Applications Immunohistochemistry
Applications Immunohistochemistry (Frozen)
Applications Immunohistochemistry (Paraffin)
Applications Immunoprecipitation
Applications Western Blotting
Host Species Rat
Cross Reactivity Mouse
Immunogen The immunogen for this antibody was MHC Class II.
Isotype IgG2b, κ
Quantity 0.5mg
Formulation Phosphate buffer pH 7.2
Conjugate Unlabeled
Storage Requirements Store at 4°C. Do not freeze.
Format Affinity Purified
Regulatory Status RUO
Antigen MHC Class II
Gene ID (Entrez) 3108
Monoclonal or Polyclonal Monoclonal
Purification Method Affinity Purified
Clone M5/114.15.2
Test Specificity The monoclonal antibody reacts with the mouse major histocompatibility complex class II, both I-A and I-E subregion-encoded glycoproteins (I-A b, I-A d, I-A q, I-E d, I-E k, not I-A f, I-A k, or I-A s). It detects a polymorphic determinant present on B cells, monocytes, macrophages, dendritic cells, and activated T lymphocytes from mice carrying the H-2 b, H-2 d, H-2 q, H-2 p, H-2 r and H-2 u but not from mice carrying the H-2 s or H-2 f haplotypes. The M5/114 mAb is reported to inhibit I-A-restricted T cell responses of the H-2 b, H-2 d, H-2 q, H-2 u but not H-2 f, H-2 k, or H-2 s haplotypes.
Concentration 0.5mg/mL
Primary or Secondary Primary