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Rat anti-MHC Class II, Clone: M5/114.15.2, Novus Biologicals™


Manufacturer: novus biologicals canada  NBP143312005MG

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 Disclaimers

For Research Use Only

Catalog No. NBP14331205

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Description & Specifications

Specifications

Applications Flow Cytometry
Applications Functional Assay
Applications Immunohistochemistry
Applications Immunohistochemistry (Frozen)
Applications Immunohistochemistry (Paraffin)
Applications Immunoprecipitation
Applications Western Blotting
Cross Reactivity Mouse
Conjugate Unlabeled
Format Affinity Purified
Formulation Phosphate buffer pH 7.2
Immunogen The immunogen for this antibody was MHC Class II.
Primary or Secondary Primary
Isotype IgG2b, κ
Antigen MHC Class II
Host Species Rat
Gene ID (Entrez) 3108
Regulatory Status RUO
Monoclonal or Polyclonal Monoclonal
Storage Requirements Store at 4°C. Do not freeze.
Test Specificity The monoclonal antibody reacts with the mouse major histocompatibility complex class II, both I-A and I-E subregion-encoded glycoproteins (I-A b, I-A d, I-A q, I-E d, I-E k, not I-A f, I-A k, or I-A s). It detects a polymorphic determinant present on B cells, monocytes, macrophages, dendritic cells, and activated T lymphocytes from mice carrying the H-2 b, H-2 d, H-2 q, H-2 p, H-2 r and H-2 u but not from mice carrying the H-2 s or H-2 f haplotypes. The M5/114 mAb is reported to inhibit I-A-restricted T cell responses of the H-2 b, H-2 d, H-2 q, H-2 u but not H-2 f, H-2 k, or H-2 s haplotypes.
Concentration 0.5mg/mL
Clone M5/114.15.2
Purification Method Affinity Purified
Quantity 0.05mg