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Rat anti-MHC Class II, Clone: M5/114.15.2, Novus Biologicals™


Manufacturer: novus biologicals canada  NBP143312005MG

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 Disclaimers

For Research Use Only

Catalog No. NBP14331205

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Description & Specifications

Specifications

Applications Flow Cytometry
Applications Functional Assay
Applications Immunohistochemistry
Applications Immunohistochemistry (Frozen)
Applications Immunohistochemistry (Paraffin)
Applications Immunoprecipitation
Applications Western Blotting
Format Affinity Purified
Formulation Phosphate buffer pH 7.2
Immunogen The immunogen for this antibody was MHC Class II.
Isotype IgG2b, κ
Primary or Secondary Primary
Conjugate Unlabeled
Cross Reactivity Mouse
Antigen MHC Class II
Host Species Rat
Regulatory Status RUO
Storage Requirements Store at 4°C. Do not freeze.
Monoclonal or Polyclonal Monoclonal
Gene ID (Entrez) 3108
Purification Method Affinity Purified
Quantity 0.05mg
Test Specificity The monoclonal antibody reacts with the mouse major histocompatibility complex class II, both I-A and I-E subregion-encoded glycoproteins (I-A b, I-A d, I-A q, I-E d, I-E k, not I-A f, I-A k, or I-A s). It detects a polymorphic determinant present on B cells, monocytes, macrophages, dendritic cells, and activated T lymphocytes from mice carrying the H-2 b, H-2 d, H-2 q, H-2 p, H-2 r and H-2 u but not from mice carrying the H-2 s or H-2 f haplotypes. The M5/114 mAb is reported to inhibit I-A-restricted T cell responses of the H-2 b, H-2 d, H-2 q, H-2 u but not H-2 f, H-2 k, or H-2 s haplotypes.
Clone M5/114.15.2
Concentration 0.5mg/mL