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Rat anti-MHC Class II, Clone: M5/114.15.2, Novus Biologicals™


Manufacturer: novus biologicals canada  NBP14331201MG

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 Disclaimers

For Research Use Only

Catalog No. NBP14331201

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Description & Specifications

Specifications

Applications Flow Cytometry
Applications Functional Assay
Applications Immunohistochemistry
Applications Immunohistochemistry (Frozen)
Applications Immunohistochemistry (Paraffin)
Applications Immunoprecipitation
Applications Western Blotting
Isotype IgG2b, κ
Storage Requirements Store at 4°C. Do not freeze.
Test Specificity The monoclonal antibody reacts with the mouse major histocompatibility complex class II, both I-A and I-E subregion-encoded glycoproteins (I-A b, I-A d, I-A q, I-E d, I-E k, not I-A f, I-A k, or I-A s). It detects a polymorphic determinant present on B cells, monocytes, macrophages, dendritic cells, and activated T lymphocytes from mice carrying the H-2 b, H-2 d, H-2 q, H-2 p, H-2 r and H-2 u but not from mice carrying the H-2 s or H-2 f haplotypes. The M5/114 mAb is reported to inhibit I-A-restricted T cell responses of the H-2 b, H-2 d, H-2 q, H-2 u but not H-2 f, H-2 k, or H-2 s haplotypes.
Purification Method Affinity Purified
Cross Reactivity Mouse
Quantity 0.1mg
Conjugate Unlabeled
Monoclonal or Polyclonal Monoclonal
Regulatory Status RUO
Formulation Phosphate buffer pH 7.2
Primary or Secondary Primary
Immunogen The immunogen for this antibody was MHC Class II.
Gene ID (Entrez) 3108
Antigen MHC Class II
Clone M5/114.15.2
Host Species Rat
Concentration 0.5mg/mL
Format Affinity Purified