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Rat anti-MHC Class II, Clone: M5/114.15.2, Novus Biologicals™


Manufacturer: novus biologicals canada  NBP14331201MG

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 Disclaimers

For Research Use Only

Catalog No. NBP14331201

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Description & Specifications

Specifications

Applications Flow Cytometry
Applications Functional Assay
Applications Immunohistochemistry
Applications Immunohistochemistry (Frozen)
Applications Immunohistochemistry (Paraffin)
Applications Immunoprecipitation
Applications Western Blotting
Isotype IgG2b, κ
Purification Method Affinity Purified
Storage Requirements Store at 4°C. Do not freeze.
Test Specificity The monoclonal antibody reacts with the mouse major histocompatibility complex class II, both I-A and I-E subregion-encoded glycoproteins (I-A b, I-A d, I-A q, I-E d, I-E k, not I-A f, I-A k, or I-A s). It detects a polymorphic determinant present on B cells, monocytes, macrophages, dendritic cells, and activated T lymphocytes from mice carrying the H-2 b, H-2 d, H-2 q, H-2 p, H-2 r and H-2 u but not from mice carrying the H-2 s or H-2 f haplotypes. The M5/114 mAb is reported to inhibit I-A-restricted T cell responses of the H-2 b, H-2 d, H-2 q, H-2 u but not H-2 f, H-2 k, or H-2 s haplotypes.
Formulation Phosphate buffer pH 7.2
Immunogen The immunogen for this antibody was MHC Class II.
Quantity 0.1mg
Regulatory Status RUO
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Conjugate Unlabeled
Cross Reactivity Mouse
Antigen MHC Class II
Format Affinity Purified
Host Species Rat
Gene ID (Entrez) 3108
Clone M5/114.15.2
Concentration 0.5mg/mL