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Thermo Scientific™ Lab Vision™ Raf-1 (Phospho-specific) Ab-2, Rat Monoclonal Antibody

Provide accurate, reproducible results with the Thermo Scientific™ Raf-1 (Phospho-specific) Ab-2, Rat Monoclonal Antibody.

$382.98 - $1,540.65

Specifications

Antigen Raf-1 (Phospho-specific) Ab-2
Clone pS338[DPR/2/2A/3A]
Applications Immunohistochemistry (Paraffin)
Classification Monoclonal
Conjugate Unlabeled
View More Specs


Products ${productFamilyLength}
Catalog Number Mfr. No. Formulation Quantity Price Quantity  
Catalog Number Mfr. No. Formulation Quantity Price Quantity  
RT1732P Thermo Scientific™ Lab Vision™
RT1732P
Purified Ab with BSA and Azide 1mL Each for $1,473.31
RT1732P0 Thermo Scientific™ Lab Vision™
RT1732P0
Purified Ab with BSA and Azide 100μL Each for $382.98
RT1732P1 Thermo Scientific™ Lab Vision™
RT1732P1
Purified Ab with BSA and Azide 500μL Each for $1,067.59
RT1732P1ABX Thermo Scientific™ Lab Vision™
RT1732P1ABX
Ab without BSA/Azide (Frozen) 100μL Each for $1,132.73
RT1732PABX Thermo Scientific™ Lab Vision™
RT1732PABX
Ab without BSA/Azide (Frozen) 200μL Each for $1,540.65
RT1732R7 Thermo Scientific™ Lab Vision™
RT1732R7
Ready-to-use for IHC (UVLP) 7mL Each for $832.69
Specifications

Description

Provide accurate, reproducible results with the Thermo Scientific™ Raf-1 (Phospho-specific) Ab-2, Rat Monoclonal Antibody.

Raf1 is an important mediator of signal transduction pathway. It is activated through activation by Src and protein kinase C. It further phosphorylates Mek1 and cdc25. It can bind to GTP-bound Ras through N-terminal domain. It also interacts with hsp90 and 14.3.3 family of proteins.

Host Species: Rat

Clone: pS338[DPR/2/2A/3A]

Isotype: IgG1

Species Reactivity: Human. Others not known.

Epitope: GQRDS™SYY™WEIEAS

Immunogen: A synthetic peptide corresponding to aa GQRDS™SYY™WEIEAS

Molecular Weight: 74kDa

Positive Control: Tonsil

Cellular Localization: Nuclear Ab-2 binds to phosphorylated serine residue at aa338. It does not bind to unactivated Raf-1 or Raf-1 phosphorylated at Y341 and S339.

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)

Note:

USA: RUO; Int'l: RUO


General References:

1. Mason C S, et al. (1999) EMBO J, 18:2137-2148.

Description & Specifications

Specifications

Raf-1 (Phospho-specific) Ab-2
Immunohistochemistry (Paraffin)
Unlabeled
RUO
Primary
IgG1
pS338[DPR/2/2A/3A]
Monoclonal
Rat
Signal Transduction
A synthetic peptide corresponding to aa GQRDSasteriskSYYasteriskWEIEAS