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Thermo Scientific™ Lab Vision™ Raf-1 (Phospho-specific) Ab-2, Rat Monoclonal Antibody

Provide accurate, reproducible results with the Thermo Scientific™ Raf-1 (Phospho-specific) Ab-2, Rat Monoclonal Antibody.

Manufacturer:  Thermo Scientific™ Lab Vision™ RT1732PABX

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Catalog No. RT1732PABX


 

Specifications

Description

Provide accurate, reproducible results with the Thermo Scientific™ Raf-1 (Phospho-specific) Ab-2, Rat Monoclonal Antibody.

Raf1 is an important mediator of signal transduction pathway. It is activated through activation by Src and protein kinase C. It further phosphorylates Mek1 and cdc25. It can bind to GTP-bound Ras through N-terminal domain. It also interacts with hsp90 and 14.3.3 family of proteins.

Host Species: Rat

Clone: pS338[DPR/2/2A/3A]

Isotype: IgG1

Species Reactivity: Human. Others not known.

Epitope: GQRDS™SYY™WEIEAS

Immunogen: A synthetic peptide corresponding to aa GQRDS™SYY™WEIEAS

Molecular Weight: 74kDa

Positive Control: Tonsil

Cellular Localization: Nuclear Ab-2 binds to phosphorylated serine residue at aa338. It does not bind to unactivated Raf-1 or Raf-1 phosphorylated at Y341 and S339.

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)

Note:

USA: RUO; Int'l: RUO

Description & Specifications

Specifications

Raf-1 (Phospho-specific) Ab-2
Monoclonal
1mg/mL
Human
Ab without BSA/Azide (Frozen)
A synthetic peptide corresponding to aa GQRDSasteriskSYYasteriskWEIEAS
200μL
Signal Transduction
Monoclonal
Immunohistochemistry (Paraffin)
pS338[DPR/2/2A/3A]
Unlabeled
Concentrated
Rat
IgG1
RUO
Primary
Human