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Thermo Scientific™ Lab Vision™ Raf-1 (Phospho-specific) Ab-2, Rat Monoclonal Antibody


Provide accurate, reproducible results with the Thermo Scientific™ Raf-1 (Phospho-specific) Ab-2, Rat Monoclonal Antibody.

Manufacturer: thermo scientific™ lab vision™  RT1732PABX

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Catalog No. RT1732PABX

  • / Each
 

Description & Specifications

Specifications

Regulatory Status RUO
Applications Immunohistochemistry (Paraffin)
Cross Reactivity Human
Quantity 200µL
Clone pS338[DPR/2/2A/3A]
Isotype IgG1
Host Species Rat
Format Concentrated
Antigen Raf-1 (Phospho-specific) Ab-2
Immunogen A synthetic peptide corresponding to aa GQRDSasteriskSYYasteriskWEIEAS
Formulation Ab without BSA/Azide (Frozen)
Type Primary
Concentration 1mg/mL
Conjugate Unlabeled
Classification Monoclonal
Research Discipline Signal Transduction

Provide accurate, reproducible results with the Thermo Scientific™ Raf-1 (Phospho-specific) Ab-2, Rat Monoclonal Antibody.

Raf1 is an important mediator of signal transduction pathway. It is activated through activation by Src and protein kinase C. It further phosphorylates Mek1 and cdc25. It can bind to GTP-bound Ras through N-terminal domain. It also interacts with hsp90 and 14.3.3 family of proteins.

Host Species: Rat

Clone: pS338[DPR/2/2A/3A]

Isotype: IgG1

Species Reactivity: Human. Others not known.

Epitope: GQRDS™SYY™WEIEAS

Immunogen: A synthetic peptide corresponding to aa GQRDS™SYY™WEIEAS

Molecular Weight: 74kDa

Positive Control: Tonsil

Cellular Localization: Nuclear Ab-2 binds to phosphorylated serine residue at aa338. It does not bind to unactivated Raf-1 or Raf-1 phosphorylated at Y341 and S339.

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)

Note:

USA: RUO; Int'l: RUO