Thermo Scientific™ Lab Vision™ Raf-1 (Phospho-specific) Ab-2, Rat Monoclonal Antibody
Provide accurate, reproducible results with the Thermo Scientific™ Raf-1 (Phospho-specific) Ab-2, Rat Monoclonal Antibody.
Manufacturer: Thermo Scientific™ Lab Vision™ RT1732P1ABX
Provide accurate, reproducible results with the Thermo Scientific™ Raf-1 (Phospho-specific) Ab-2, Rat Monoclonal Antibody.Raf1 is an important mediator of signal transduction pathway. It is activated through activation by Src and protein kinase C. It further phosphorylates Mek1 and cdc25. It can bind to GTP-bound Ras through N-terminal domain. It also interacts with hsp90 and 14.3.3 family of proteins.
Host Species: Rat
Species Reactivity: Human. Others not known.
Immunogen: A synthetic peptide corresponding to aa GQRDS™SYY™WEIEAS
Molecular Weight: 74kDa
Positive Control: Tonsil
Cellular Localization: Nuclear Ab-2 binds to phosphorylated serine residue at aa338. It does not bind to unactivated Raf-1 or Raf-1 phosphorylated at Y341 and S339.
- Immunohistochemistry (Formalin/paraffin)
USA: RUO; Int'l: RUO
|Raf-1 (Phospho-specific) Ab-2|
|Ab without BSA/Azide (Frozen)|
|A synthetic peptide corresponding to aa GQRDSasteriskSYYasteriskWEIEAS|