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Tocris™ (R)-DRF053 dihydrochloride

Dual CK1/cdk inhibitor

$309.99 - $1,284.01

Specifications

Product Type (R)-DRF053 dihydrochloride
Inhibitors (R)-DRF053 dihydrochloride
Molecular Weight 490.43
Purity >98
View More Specs

Disclaimers:

For Research Use Only



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
361010R Tocris™
361010
10mg Each for $309.99
361050R Tocris™
361050
50mg Each for $1,284.01
Specifications

Description

Potent, ATP-competitive inhibitor of cyclin-dependent kinase (cdk) and casein kinase 1 (CK1) (IC50 values are 220, 80 and 14nM for cdk1/cyclin B, cdk5/p25 and CK1 respectively). Selective over GSK-3 αβ (IC50= 4.1μM). Also shown to inhibit amyloid-β production in N2A-APP695 cells.
  • Chemical Name: 2-[[9-(1-Methylethyl)-6-[[3-(2-pyridinyl)phenyl]amino]-9H-purin-2-yl]amino]-1-butanol dihydrochloride
  • Formula: C23H27N7O.2HCl
  • CAS Number: 1241675-76-2
  • Solubility: Soluble to 100mM in water and to 100mM in DMSO
  • Purity: >98
Description & Specifications

Specifications

(R)-DRF053 dihydrochloride
(R)-DRF053 dihydrochloride
490.43
>98