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Alfa Aesar™ (R)-(-)-Deprenyl hydrochloride

Selective MAO-B inhibitor; anti-Parkinsonian agent

$105.18 - $305.34

Chemical Identifiers

CAS 14611-52-0
Molecular Formula C13H18ClN
Molecular Weight (g/mol) 223.744
MDL Number MFCD00069299
InChI Key IYETZZCWLLUHIJ-UTONKHPSSA-N
Synonym selegiline hydrochloride, eldepryl, zelapar, selegiline hcl, l-deprenyl hydrochloride, jumex hydrochloride, --deprenyl hydrochloride, eldepryl hydrochloride, r-n-methyl-n-1-phenylpropan-2-yl prop-2-yn-1-amine hydrochloride, zydis selegiline
PubChem CID 26758
ChEBI CHEBI:9087
IUPAC Name (2R)-N-methyl-1-phenyl-N-prop-2-ynylpropan-2-amine;hydrochloride
SMILES CC(CC1=CC=CC=C1)N(C)CC#C.Cl
View More Specs

Products 2
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
AAJ61286MD View Documents Alfa Aesar™
J61286MD
250mg Each for $105.18
 
AAJ6128603 View Documents Alfa Aesar™
J6128603
1g Each for $305.34
 
Description

Description

Applications
(R)-(-)-Deprenyl hydrochloride provides neuroprotection which may be relevant to Parkinson’s disease, Alzheimer’s disease, Huntington’s disease, and stroke. It is an inhibitor of MAO-B (monoamine oxidase-B) which demonstrates extensive neuroprotective effects shown to be uncorrelated with MAO-B inhibiting activity. It demonstrates protection of dopaminergic neurons from excitotoxicity mediated by NMDA activation. It also demonstrates decreases in apoptosis of PC12 neuronal cells accompanied with an induction of new protein synthesis through direct transcriptional and translational interaction, and reduced cell death and internucleosomal DNA degredation at concentrations too low to inhibit MAO-B.

Solubility
Soluble in water at 100mM

Notes
Stable under recommended storage conditions. Incompatible with oxidizing agents.
Specifications

Chemical Identifiers

14611-52-0
223.744
IYETZZCWLLUHIJ-UTONKHPSSA-N
26758
(2R)-N-methyl-1-phenyl-N-prop-2-ynylpropan-2-amine;hydrochloride
C13H18ClN
MFCD00069299
selegiline hydrochloride, eldepryl, zelapar, selegiline hcl, l-deprenyl hydrochloride, jumex hydrochloride, --deprenyl hydrochloride, eldepryl hydrochloride, r-n-methyl-n-1-phenylpropan-2-yl prop-2-yn-1-amine hydrochloride, zydis selegiline
CHEBI:9087
CC(CC1=CC=CC=C1)N(C)CC#C.Cl

Specifications

−12° (c=1 in Water)
250mg
C13H18ClN
14,8428
Soluble in water at 100mM
CC(CC1=CC=CC=C1)N(C)CC#C.Cl
223.744
CHEBI:9087
Crystalline Powder
White
14611-52-0
MFCD00069299
selegiline hydrochloride, eldepryl, zelapar, selegiline hcl, l-deprenyl hydrochloride, jumex hydrochloride, --deprenyl hydrochloride, eldepryl hydrochloride, r-n-methyl-n-1-phenylpropan-2-yl prop-2-yn-1-amine hydrochloride, zydis selegiline
IYETZZCWLLUHIJ-UTONKHPSSA-N
(2R)-N-methyl-1-phenyl-N-prop-2-ynylpropan-2-amine;hydrochloride
26758
223.74
(R)-(-)-Deprenyl hydrochloride
Safety and Handling

Safety and Handling

GHS H Statement
H315-H319
Causes skin irritation.
Causes serious eye irritation.

GHS P Statement
P280-P305+P351+P338-P362-P321-P332+P313-P337+P313
Wear protective gloves/protective clothing/eye protection/face protection.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Take off contaminated clothing and wash before reuse.
Specific treatment (see label).
If skin irritation occurs: Get medical advice/attention.
If eye irritation persists: Get medical advice/attention.

Warning

RTECSNumber : DA0292500