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Alfa Aesar™ (R)-(-)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetyl chloride, 98+%

Chemical Identifiers

Chemical Name or Material (R)-(-)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetyl chloride
CAS 39637-99-5
Molecular Formula C10H8ClF3O2
Formula Weight 252.62
MDL Number MFCD00044400
UN Number UN3265
Beilstein 3591565
Merck Index 14,6280
Synonym (R)-(-)-Mosher's acid chloride; (R)-(-)-MTPA-Cl
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Products
Catalog Number Mfr. No. Quantity Price Quantity    

AAL1432503

  SDS
alfa aesar™
L1432503
1g CALL N/A N/A
 Please call Customer Service at 1-800-234-7437 or send an email to help@thermofisher.com for assistance.

AAL14325MD

  SDS
alfa aesar™
L14325MD
250mg CALL N/A N/A
 Please call Customer Service at 1-800-234-7437 or send an email to help@thermofisher.com for assistance.

AAL14325MF

  SDS
alfa aesar™
L14325MF
50mg CALL N/A N/A
 Please call Customer Service at 1-800-234-7437 or send an email to help@thermofisher.com for assistance.
Description & Specifications

Specifications

Formula Weight 252.62
Chemical Name or Material (R)-(-)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetyl chloride
Molecular Formula C10H8ClF3O2
Assay ≥98%
CAS 39637-99-5
Health Hazard 3 GHS P Statement
P210-P260-P303+P361+P353-P305+P351+P338-P405-P501a
Keep away from heat/sparks/open flames/hot surfaces. - No smoking.
Do not breathe dust/fume/gas/mist/vapors/spray.
IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.
UN Number UN3265
MDL Number MFCD00044400
Merck Index 14,6280
Synonym (R)-(-)-Mosher's acid chloride; (R)-(-)-MTPA-Cl
Health Hazard 2 GHS H Statement
H314-H318-H227
Causes severe skin burns and eye damage.
Causes serious eye damage.
Combustible liquid.
Health Hazard 1 Danger
DOT Information Transport Hazard Class: 8; Packing Group: II; Proper Shipping Name: CORROSIVE LIQUID, ACIDIC, ORGANIC, N.O.S.
Recommended Storage −30° to −10°C
Quantity 1g
Optical Rotation −137° (Neat)
Beilstein 3591565
Boiling Point 213° to 214°C
Flash Point 89°C (192°F)

Applications
(R)-(-)-α-Methoxy-α-(trifluoromethyl)phenylacetyl chloride is used as a chiral acylating reagent, which is used in the resolution of amino acid enantiomers like 2,5-dimethoxy-4-methylamphetamine. It is also suitable for the determination of the optical composition of compounds extracted from biological fluids.

Solubility
Sparingly miscible with water.

Notes
Moisture sensitive. Store in a cool place. Keep the container tightly closed in a dry and well-ventilated place.

Safety and Handling

Danger

GHS P Statement
P210-P260-P303+P361+P353-P305+P351+P338-P405-P501a
Keep away from heat/sparks/open flames/hot surfaces. - No smoking.
Do not breathe dust/fume/gas/mist/vapors/spray.
IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.

GHS H Statement
H314-H318-H227
Causes severe skin burns and eye damage.
Causes serious eye damage.
Combustible liquid.

−30° to −10°C