(R)-(+)-3-Hydroxypyrrolidine is used in the enantioselective addition of diethylzinc to aromatic aldehydes leading to optically active secondary alcohols. Also used to prepare-κ-opioid receptor agonists.
Soluble in water and methanol.
Store under inert gas. It is sensitive to moisture. Store in a cool, dry conditions in well sealed containers. It is hygroscopic and sensitive to air. Incompatible with oxidizing agents.
|+6.5° (c=3.5 in Methanol)|
|99%, ee 99%|
|108° to 110°C (8mmHg)|
Safety and Handling
GHS H Statement
Causes skin irritation.
Causes serious eye irritation.
GHS P Statement
Wear protective gloves/protective clothing/eye protection/face protection.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Take off contaminated clothing and wash before reuse.
Specific treatment (see label).
If skin irritation occurs: Get medical advice/attention.
If eye irritation persists: Get medical advice/attention.